caa a22 4500 386322694 CHVBK 20180307111632.0 cr unu---uuuuu 161130e198803 xx s 000 0 eng 10.1079/BJN19880034 doi S0007114588000352 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880034 Cunnane Stephen C. Department of Nutritional Sciences, University of Toronto, Toronto, Canada M5S 1A8 Evidence that adverse effects of zinc deficiency on essential fatty acid composition in rats are independent of food intake [Elektronische Daten] [Stephen C. Cunnane] 1. Young male rats were fed on diets containing 3·4, 36 or 411 mg zinc/kg for 10 weeks in order to determine whether effects of Zn deficiency on plasma and liver essential fatty acid composition could be distinguished from those of reduced protein and energy intake. 2. Fatty acid analysis revealed that a Zn intake of 3·4 mg/kg (plasma Zn 0·80 v. 1·97 mmol/l in controls fed on 36 mg Zn/kg) resulted in a significant increase in the linoleic acid: arachidonic acid ratio in both plasma and liver phospholipids in comparison with rats fed on 36 or 411 mg Zn/kg. 3. Zn supplementation (411 mg/kg) decreased the linoleic acid: arachidonic acid ratio in plasma phosphatidylserine compared with that of the controls. 4. The previously reported increase in arachidonic acid (mol %) in liver triacylglycerol of Zn-deficient rats was shown to be a function of a reduced liver triacylglycerol pool size; quantitatively, triacylglycerol content of arachidonic acid in the liver was not significantly affected by Zn intake. Copyright © The Nutrition Society 1988 British Journal of Nutrition Cambridge University Press 59/2(1988-03), 273-278 0007-1145 59:2<273 1988 59 BJN https://doi.org/10.1079/BJN19880034 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880034 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Cunnane Stephen C. Department of Nutritional Sciences, University of Toronto, Toronto, Canada M5S 1A8 NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 59/2(1988-03), 273-278 0007-1145 59:2<273 1988 59 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge