caa a22 4500 386322775 CHVBK 20180307111632.0 cr unu---uuuuu 161130e198803 xx s 000 0 eng 10.1079/BJN19880024 doi S000711458800025X pii (NATIONALLICENCE)cambridge-10.1079/BJN19880024 Selenium balance studies in apparently healthy and housebound elderly people eating self-selected diets [Elektronische Daten] 1. Metabolic balance studies (5 d) for Se were conducted in twenty-four apparently healthy elderly people (age 69·6-85·4 years), and twenty housebound subjects (age 69·9-85·1 years) with chronic disease. During the study the subjects lived in their own homes, ate self-selected diets and continued their normal daily activities. 2. Geometric mean daily dietary intakes of the two groups were significantly different (P < 0·01), being 819 (range 310-1631) nmol for the healthy and 475 (range 233-1136) nmol for the housebound elderly. 3. Daily intake of Se significantly correlated with balance in both groups. Solution of the regression equations gave theoretical daily requirements of 447 nmol for the healthy and 419 nmol for the housebound subjects. The healthy elderly were in positive balance of 148 nmol/d for Se and the housebound were in equilibrium with an overall mean retention of 43 nmol/d. 4. Mean levels of Se in blood fractions for the healthy and housebound subjects were significantly different, being 1·65 and 1·40 μmol/l whole blood, 1·45 and 1·21 μmol/l plasma and 5·72 and 5·30 nmol/g haemoglobin in erythrocytes respectively. There was no difference in the whole-blood glutathione peroxidase (EC 1.11.1.9) activities between the two groups. 5. There were clear differences in Se status between the two groups of elderly people. The cause of the positive balance in the healthy subjects remains unexplained. Copyright © The Nutrition Society 1988 Bunker Valda W. Chemical Pathology and Human Metabolism,Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY Lawson Margaret S. Department of Applied Chemistry and Life Sciences, The Polytechnic of North London, London N8 7DB Stansfield Maureen F. Geriatric Medicine, Medical Faculty of the University of Southampton, Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY Clayton Barbara E. Chemical Pathology and Human Metabolism,Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY British Journal of Nutrition Cambridge University Press 59/2(1988-03), 171-180 0007-1145 59:2<171 1988 59 BJN https://doi.org/10.1079/BJN19880024 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880024 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bunker Valda W. Chemical Pathology and Human Metabolism,Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY NATIONALLICENCE 700 1- Lawson Margaret S. Department of Applied Chemistry and Life Sciences, The Polytechnic of North London, London N8 7DB NATIONALLICENCE 700 1- Stansfield Maureen F. Geriatric Medicine, Medical Faculty of the University of Southampton, Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY NATIONALLICENCE 700 1- Clayton Barbara E. Chemical Pathology and Human Metabolism,Level D, South Laboratory Block, Southampton General Hospital, Southampton SO9 4XY NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 59/2(1988-03), 171-180 0007-1145 59:2<171 1988 59 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge