caa a22 4500 386322929 CHVBK 20180307111633.0 cr unu---uuuuu 161130e198811 xx s 000 0 eng 10.1079/BJN19880116 doi S0007114588001187 pii (NATIONALLICENCE)cambridge-10.1079/BJN19880116 Driver Christopher J. I. Department of Science, Victoria College, Rusden Campus, 662 Blackburn Rd, Clayton, Victoria 3168, Australia The effect of meal composition on the degree of satiation following a test meal and possible mechanisms involved [Elektronische Daten] [Christopher J. I. Driver] 1. Possible links between metabolism and satiation were investigated using volunteer subjects given test meals based on milk solids. Satisfaction was rated by the subjects on a six-point scale and the course of metabolism was followed by measurement of the respiratory quotient (RQ). 2. The time-course of satiation was the same for a high-carbohydrate, a high-fat and a high-protein meal, in spite of the very different time-course of metabolism. The degree of satiation was reduced by added sodium chloride, without affecting the RQ rise. On the other hand, calcium chloride produced a suppression of the RQ rise without altering the satiation. 3. It is proposed that the results indicate that the primary receptors responsible for post-prandial satiation lie within the gut wall and that there is probably a number of receptor types. Likely candidates for these receptors are the gut hormone-secreting cells. 4. Although very-low-protein meals produce less satiation than meals containing 220 g protein/kg dry weight, there is no additional satiation obtained by increasing the protein level further. This is not inconsistent with the possibility of a protein hunger separate from an energy hunger. Copyright © The Nutrition Society 1988 British Journal of Nutrition Cambridge University Press 60/3(1988-11), 441-449 0007-1145 60:3<441 1988 60 BJN https://doi.org/10.1079/BJN19880116 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19880116 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Driver Christopher J. I. Department of Science, Victoria College, Rusden Campus, 662 Blackburn Rd, Clayton, Victoria 3168, Australia NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 60/3(1988-11), 441-449 0007-1145 60:3<441 1988 60 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge