caa a22 4500 386347190 CHVBK 20180307111815.0 cr unu---uuuuu 161130e198912 xx s 000 0 eng 10.1017/S0022215100111314 doi S0022215100111314 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100111314 Wegener's granulomatosis, subglottic stenosis and antineutrophil cytoplasm antibodies [Elektronische Daten] Wegener's granulomatosis is difficult to diagnose, especially when the presentation is unusual, restricted to an isolated region. We report four cases of recurrent subglottic stenosis posing difficulty in diagnosis. In each case the finding of anti-neutrophil cytoplasm antibodies (ANCA) strongly suggested an underlying vasculitic pathology, Wegener's granulomatosis. We discuss reasons for the difficulty in diagnosis in the past, the possible role of the ANCA assay in such patients, and suggest it should be more widely used in the future. Copyright © JLO (1984) Limited 1989 Hoare T. J. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA Jayne D. University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ Evans P. Rhys Royal Marsden Hospital, Fulham Road, London SW3 Croft C. B. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA Howard D. J. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA The Journal of Laryngology & Otology Cambridge University Press 103/12(1989-12), 1187-1191 0022-2151 103:12<1187 1989 103 JLO https://doi.org/10.1017/S0022215100111314 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100111314 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hoare T. J. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA NATIONALLICENCE 700 1- Jayne D. University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ NATIONALLICENCE 700 1- Evans P. Rhys Royal Marsden Hospital, Fulham Road, London SW3 NATIONALLICENCE 700 1- Croft C. B. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA NATIONALLICENCE 700 1- Howard D. J. Royal National Throat Nose and Ear Hospital, Grays Inn Road, London WC1X8DA NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 103/12(1989-12), 1187-1191 0022-2151 103:12<1187 1989 103 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge