caa a22 4500 386347409 CHVBK 20180307111816.0 cr unu---uuuuu 161130e198908 xx s 000 0 eng 10.1017/S0022215100109958 doi S0022215100109958 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100109958 Nasal decongestant effect of oxymetazoline in the common cold: An objective dose-response study in 106 patients [Elektronische Daten] Oxymetazoline has been used as decongesting nosedrops for more than 25 years but so far no objective does-response study of the drug has been published. In this double-blind clinical trial the decongestant effect on the nasal mucosa by the doses and concentrations traditionally used of oxymetazoline were studied. In 106 men with acute infectious rhinitis, a significant dose-response relationship was found when the decongestant effect was measured objectively by anterior rhinomanometry and subjectively by symptom scores. The concentration and volumes of the drug recommended from clinical experience seem to be adequate. Copyright © JLO (1984) Limited 1989 Åkerland Anders From the Department of Otorinolaryngology, Central Hospital, Sköevde Klint Thorsten Department of Clinical Research, AB Draco, Lund, Sweden Olén Lars From the Department of Otorinolaryngology, Central Hospital, Sköevde Rundcrantz Hans From the Department of Otorinolaryngology, Central Hospital, Sköevde The Journal of Laryngology & Otology Cambridge University Press 103/8(1989-08), 743-746 0022-2151 103:8<743 1989 103 JLO https://doi.org/10.1017/S0022215100109958 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100109958 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Åkerland Anders From the Department of Otorinolaryngology, Central Hospital, Sköevde NATIONALLICENCE 700 1- Klint Thorsten Department of Clinical Research, AB Draco, Lund, Sweden NATIONALLICENCE 700 1- Olén Lars From the Department of Otorinolaryngology, Central Hospital, Sköevde NATIONALLICENCE 700 1- Rundcrantz Hans From the Department of Otorinolaryngology, Central Hospital, Sköevde NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 103/8(1989-08), 743-746 0022-2151 103:8<743 1989 103 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge