caa a22 4500 386348383 CHVBK 20180307111819.0 cr unu---uuuuu 161130e198905 xx s 000 0 eng 10.1017/S0022215100156750 doi S0022215100156750 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100156750 Recovery from sensorineural deafness in Wegener's granulomatosis [Elektronische Daten] Wegener's granulomatosis may present with deafness or other aural symptoms. This report describes two patients with histological evidence of Wegener's granulomatosis who developed reversible sensorineural hearing loss during the course of their illness. The first patient showed complete recovery of a sensorineural hearing loss averaging 50 dB after ten months treatment with cyclophosphamide and high-dose prednisolone. The second patient, who was on maintenance haemodialysis, achieved a 40 dB improvement in sensorineural hearing loss within two weeks of adding cyclophosphamide to pre-existing corticosteroid therapy. These findings suggest that the prognosis of sensorineural hearing loss in Wegener's granulomatosis can be improved with suppression of the vasculitic process by early treatment with combined cytotoxic-immunosuppressive therapy Copyright © JLO (1984) Limited 1989 Clements M. R. Lecturer, University Department of Medicine, Royal Infirmary, Manchester Mistry C. D. Senior Registrar, Renal Unit, Royal Infirmary, Manchester Keith A. O. Senior Registrar, University Department of Otolaryngology, Royal Infirmary, Manchester Ramsden R. T. Consultant Otolaryngologist, University Department of Otolaryngology, Royal Infirmary, Manchester. The Journal of Laryngology & Otology Cambridge University Press 103/5(1989-05), 515-518 0022-2151 103:5<515 1989 103 JLO https://doi.org/10.1017/S0022215100156750 text/html Onlinezugriff via DOI 1 other jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100156750 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Clements M. R. Lecturer, University Department of Medicine, Royal Infirmary, Manchester NATIONALLICENCE 700 1- Mistry C. D. Senior Registrar, Renal Unit, Royal Infirmary, Manchester NATIONALLICENCE 700 1- Keith A. O. Senior Registrar, University Department of Otolaryngology, Royal Infirmary, Manchester NATIONALLICENCE 700 1- Ramsden R. T. Consultant Otolaryngologist, University Department of Otolaryngology, Royal Infirmary, Manchester NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 103/5(1989-05), 515-518 0022-2151 103:5<515 1989 103 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge