caa a22 4500 386348561 CHVBK 20180307111820.0 cr unu---uuuuu 161130e198901 xx s 000 0 eng 10.1017/S0022215100108011 doi S0022215100108011 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100108011 Ototoxicity of ear drops in patients suffering from chronic otitis media [Elektronische Daten] The sensorineural hearing loss in 150 patients with chronic otitis media who were treated in the Haifa Medical Center (Rothschild) during a ten year period was studied. There were 124 patients treated with a mixture containing neomycin, polymyxin B and dexamethasone and a control group of 26 patients with dexamethasone only. All patients were followed up for a period of 1-2 years. Patients with hearing loss due to factors such as previous ear surgery, family history, exposure to noise etc., have been excluded. The conclusions reached were that there is a relationship between the period of disease and the sensorineural hearing loss and that the local treatment with a mixture containing neomycin + polymyxin B appears to contribute to the worsening of the sensorineural hearing loss in patients with chronic otitis media. Our numbers are small and further studies must be done, but the fact that currently used ear drops may produce a sensorineural hearing loss should not be ignored. Copyright © JLO (1984) Limited 1989 Podoshin L. From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel. Fradis M. From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel. David J. Ben From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel. The Journal of Laryngology & Otology Cambridge University Press 103/1(1989-01), 46-50 0022-2151 103:1<46 1989 103 JLO https://doi.org/10.1017/S0022215100108011 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100108011 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Podoshin L. From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel NATIONALLICENCE 700 1- Fradis M. From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel NATIONALLICENCE 700 1- David J. Ben From the Department of Otolaryngology, Haifa Medical Center (Rothschild), Faculty of Medicine, Tehnion-Israel Institute of Technology, Haifa, Israel NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 103/1(1989-01), 46-50 0022-2151 103:1<46 1989 103 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge