caa a22 4500 386348863 CHVBK 20180307111821.0 cr unu---uuuuu 161130e198901 xx s 000 0 eng 10.1017/S0022215100107959 doi S0022215100107959 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100107959 Does severe water deprivation affect the inner ear? [Elektronische Daten] An experimental study of the gerbilline endolyphatic sac Through an ultrastructural study of the endolymphatic duct (ED) and sac (ES) system, the effects of an impaired body fluid metabolism on the inner ear fluid environment in the mongolian gerbil has been evaluated. A dehydrative state has been determined depriving of water for both five and twelve days this desert animal, which is known to withstand long periods of water abstinence. The morphological changes of the ED and ES under these circumstances have been compared with those induced by ethacrynic acid intoxication. Although the cochlear partition did not show signs of damage, the ED and ES system seems to be negatively influenced by the dehydrative state and displays a marked imbibition of the subepithelial tissue, which at places shows accumulation of an organic matrix. A regulating role for the antidiuretic hormone on the inner ear fluids of the mongolian gerbil is also proposed and discussed. Copyright © JLO (1984) Limited 1989 Barbara M. Department of Otolaryngology, University ‘La Sapienza', Rome, Italy Bagger-Sjöbäck D. Department of Otolaryngology, Karolinska Hospital, Stockhom, Sweden Rask-Andersen H. Department of Otolaryngology, Akademiska Hospital, Uppsala, Sweden. Filipo R. Department of Otolaryngology, University ‘La Sapienza', Rome, Italy The Journal of Laryngology & Otology Cambridge University Press 103/1(1989-01), 22-29 0022-2151 103:1<22 1989 103 JLO https://doi.org/10.1017/S0022215100107959 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100107959 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Barbara M. Department of Otolaryngology, University ‘La Sapienza', Rome, Italy NATIONALLICENCE 700 1- Bagger-Sjöbäck D. Department of Otolaryngology, Karolinska Hospital, Stockhom, Sweden NATIONALLICENCE 700 1- Rask-Andersen H. Department of Otolaryngology, Akademiska Hospital, Uppsala, Sweden NATIONALLICENCE 700 1- Filipo R. Department of Otolaryngology, University ‘La Sapienza', Rome, Italy NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 103/1(1989-01), 22-29 0022-2151 103:1<22 1989 103 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge