caa a22 4500 386352771 CHVBK 20180307111839.0 cr unu---uuuuu 161130e198908 xx s 000 0 eng 10.1017/S0033291700024247 doi S0033291700024247 pii (NATIONALLICENCE)cambridge-10.1017/S0033291700024247 Predicting relapse in schizophrenia: the development and implementation of an early signs monitoring system using patients and families as observers, a preliminary investigation [Elektronische Daten] Recognition of prodromal symptoms of schizophrenia offers the potential of early intervention to avert relapse and re-hospitalization (Carpenter & Heinrichs, 1983). The present study investigated how a strategy to detect prodromal signs might be effectively applied in the clinical setting. A standard monitoring system was developed involving completion of a new early signs scale (ESS) measuring changes in key symptoms phenomenologically (self-report) and behaviourally (observer report). The ESS was subject to rigorous psychometric evaluation and tested in a prospective pilot investigation. The ESS reliably identified early signs and predicted relapse with an overall accuracy of 79%. Several different patterns of relapse were identified. Observer reports compensated for loss of insight in some patients. In two cases where early signs indices were detected, prompt increases in medication appeared to arrest relapse and avert readmission. The ESS offers itself as a reliable, valid and administratively feasible measure and demonstrates considerable potential as a cost-effective procedure for secondary prevention. Copyright © Cambridge University Press 1989 Birchwood Max Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Smith Jo Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Macmillan Fiona Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Hogg Bridget Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Prasad Rekha Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Harvey Cathy Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Bering Sandy Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham Psychological Medicine Cambridge University Press 19/3(1989-08), 649-656 0033-2917 19:3<649 1989 19 PSM https://doi.org/10.1017/S0033291700024247 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0033291700024247 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Birchwood Max Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Smith Jo Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Macmillan Fiona Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Hogg Bridget Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Prasad Rekha Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Harvey Cathy Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 700 1- Bering Sandy Department of Clinical Psychology and Academic Unit, All Saints Hospital, Birmingham NATIONALLICENCE 773 0- Psychological Medicine Cambridge University Press 19/3(1989-08), 649-656 0033-2917 19:3<649 1989 19 PSM CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge