caa a22 4500 386353743 CHVBK 20180307111843.0 cr unu---uuuuu 161130e198902 xx s 000 0 eng 10.1017/S0033291700011077 doi S0033291700011077 pii (NATIONALLICENCE)cambridge-10.1017/S0033291700011077 Distinct memory impairments following electroconvulsive therapy and imipramine [Elektronische Daten] Memory functioning was assessed in 26 unmedicated patients with major depressive disorder (DSM-III) who were then administered either bilateral electroconvulsive therapy (ECT) (N = 16) or imipramine 200 mg per day (N = 10). The subjects were retested following seven ECT administrations or 21 days of imipramine treatment respectively. The retrograde memory tasks included recall of public and autobiographic events. The anterograde memory tasks included an immediate memory task, a verbal paired-associates recall task, and a non-verbal figure reproduction task. Depression was significantly improved in the ECT-treated subjects but not in those administered imipramine. Both ECT- and imipramine-treated patients showed a deficit in recent anterograde memory relative to their pretreatment performance, but no deficit in immediate memory. ECT-treated patients also had a significant and well-characterized impairment in retrograde remote memory. By contrast, imipramine-treated patients did not show a retrograde memory impairment which could be explained by treatment. The results suggest qualitatively different memory deficits produced by ECT and imipramine. Copyright © Cambridge University Press 1989 Calev Avraham Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Ben-Tzvi Edna Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Shapira Baruch Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Drexler Heinz Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Carasso Refael Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Lerer Bernard Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel Psychological Medicine Cambridge University Press 19/1(1989-02), 111-119 0033-2917 19:1<111 1989 19 PSM https://doi.org/10.1017/S0033291700011077 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0033291700011077 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Calev Avraham Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 700 1- Ben-Tzvi Edna Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 700 1- Shapira Baruch Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 700 1- Drexler Heinz Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 700 1- Carasso Refael Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 700 1- Lerer Bernard Jerusalem Mental Health Center - Ezrat-Nashim Hospital, Jerusalem and Bar-Ilan University, Ramat Gan, Israel NATIONALLICENCE 773 0- Psychological Medicine Cambridge University Press 19/1(1989-02), 111-119 0033-2917 19:1<111 1989 19 PSM CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge