caa a22 4500 386381100 CHVBK 20180307112042.0 cr unu---uuuuu 161130e198908 xx s 000 0 eng 10.1017/S0033583500002973 doi S0033583500002973 pii (NATIONALLICENCE)cambridge-10.1017/S0033583500002973 DNA-carcinogen interaction: covalent DNA-adducts of benzo(a)pyrene 7, 8-dihydrodiol 9, 10-epoxides studied by biochemical and biophysical techniques [Elektronische Daten] Exposure to various chemicals, either due to occupation or lifestyle, is considered to be a major contributing factor to tumour formation in man (Higginson, 1969; Doll and Peto, 1981). An important and prevalent class of potent carcinogenic compounds present in he environment is polycyclic aromatic hydrocarbons (PAHs), which are found in various petroleum and combustion products derived from heat and power generation and motor vehicle exhausts (Baum, 1978). Furthermore, since PAHs are generally formed by pyrolysis of organic matters such as tobacco smoking and certain procedures of food preparation, the PAH exposure to humans is extensive. Copyright © Cambridge University Press 1989 Gräslund Astrid Department of Medical Biophysics, University of Umed, S-901 87 Umeå, Sweden Jernström Bengt Department of Toxicology, Karolinska Institutet, S-104 01 Stockholm, Sweden Quarterly Reviews of Biophysics Cambridge University Press 22/3(1989-08), 1-37 0033-5835 22:3<1 1989 22 QRB https://doi.org/10.1017/S0033583500002973 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0033583500002973 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gräslund Astrid Department of Medical Biophysics, University of Umed, S-901 87 Umeå, Sweden NATIONALLICENCE 700 1- Jernström Bengt Department of Toxicology, Karolinska Institutet, S-104 01 Stockholm, Sweden NATIONALLICENCE 773 0- Quarterly Reviews of Biophysics Cambridge University Press 22/3(1989-08), 1-37 0033-5835 22:3<1 1989 22 QRB CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence SWISSBIB 386381089 BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge