caa a22 4500 386387982 CHVBK 20180307112105.0 cr unu---uuuuu 161130e198909 xx s 000 0 eng 10.1017/S0022149X00009068 doi S0022149X00009068 pii (NATIONALLICENCE)cambridge-10.1017/S0022149X00009068 The immune response of male DSN hamsters to a primary infection with Ancylostoma ceylanicum [Elektronische Daten] The immune response of hamsters to a chronic hookworm infection has been investigated. Ancylostoma ceylanicum caused long term infections in hamsters which were associated with prominent changes in secondary lymphoid organs. The mesenteric lymph nodes and spleens increased rapidly in size stabilizing at approximately 3-4 times the weight in control animals by weeks 3-7. Cells from both the mesenteric lymph node and spleen, after an initial period of increased blast cell activity, became less reactive in the latter stages of infection. Serum antibody responses were marked, commencing in weeks 3-4 and increasing in intensity throughout the 10 week period of measurement. The results are discussed in relation to their contribution to the understanding of human hookworm infection. Copyright © Cambridge University Press 1989 Ancylostoma ceylanicum nationallicence hamster nationallicence immune response nationallicence primary infection nationallicence Garside Paul MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK Behnke Jerzy M. MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK Rose Richard A. MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK Journal of Helminthology Cambridge University Press 63/3(1989-09), 251-260 0022-149X 63:3<251 1989 63 JHL https://doi.org/10.1017/S0022149X00009068 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022149X00009068 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Garside Paul MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK NATIONALLICENCE 700 1- Behnke Jerzy M. MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK NATIONALLICENCE 700 1- Rose Richard A. MRC Experimental Parasitology Research Group, Department of Zoology, University of Nottingham, Nottingham NG7 2RD, UK NATIONALLICENCE 773 0- Journal of Helminthology Cambridge University Press 63/3(1989-09), 251-260 0022-149X 63:3<251 1989 63 JHL CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge