caa a22 4500 386388377 CHVBK 20180307112106.0 cr unu---uuuuu 161130e198903 xx s 000 0 eng 10.1017/S0022149X00008683 doi S0022149X00008683 pii (NATIONALLICENCE)cambridge-10.1017/S0022149X00008683 Hymenolepis murissylvatici: humoral response in intestinal lavages of the mouse [Elektronische Daten] Hymenolepis murissylvatici elicits a humoral response in serum and in the intestine of the mouse from which it is immunologically rejected. In serum, significant differences were recorded 3 days after reinfection, while in intestinal lavages it takes place from day 9 after reinfection. In serum the response is largely the result of IgG and IgM antibodies whereas in the intestine, IgA is the most abundant antibody. Although specific IgE could not be demonstrated in serum, it was present in intestinal lavages, although rather late (i.e. day 14 after reinfection). Treatment of young worms in vitro both with immune serum or intestinal lavages had no apparent effect on their viability. Immune serum produced a complement independent precipitation on the surface of the worms in vitro. This reaction did not affect viability or infectivity of the parasite, as demonstrated by the successful implantation of treated worms in recipient mice. The above-mentioned results, together with the knowledge that the Hymenolepis model has no tissue stages and causes no tissue damage, make it probable that further study of this model will reveal some specific intestinal immunological reactions. Copyright © Cambridge University Press 1989 Hymenolepis murissylvatici nationallicence immunoglobulins nationallicence humoral response nationallicence mouse nationallicence intestine nationallicence Van Der Vorst E. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium Dhont H. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium Van Haeren C. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium Deceunynck R. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium De Rycke P. H. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium Journal of Helminthology Cambridge University Press 63/1(1989-03), 25-31 0022-149X 63:1<25 1989 63 JHL https://doi.org/10.1017/S0022149X00008683 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022149X00008683 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Van Der Vorst E. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium NATIONALLICENCE 700 1- Dhont H. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium NATIONALLICENCE 700 1- Van Haeren C. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium NATIONALLICENCE 700 1- Deceunynck R. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium NATIONALLICENCE 700 1- De Rycke P. H. Laboratory of Zoophysiology, State University of Gent, K.L. Ledeganckstraat 35, B-9000 Gent, Belgium NATIONALLICENCE 773 0- Journal of Helminthology Cambridge University Press 63/1(1989-03), 25-31 0022-149X 63:1<25 1989 63 JHL CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge