caa a22 4500 386392994 CHVBK 20180307112126.0 cr unu---uuuuu 161130e198908 xx s 000 0 eng 10.1017/S0016672300028330 doi S0016672300028330 pii (NATIONALLICENCE)cambridge-10.1017/S0016672300028330 Interaction of Hairless, Delta, Enhancer of split and Notch genes of Drosophila melanogaster as expressed in adult morphology [Elektronische Daten] The interaction of three neurogenic loci viz. Delta, Enhancer of split and Notch, and a related gene, Hairless, of Drosophila melanogaster was investigated at the adult morphology level by measuring the effects of the mutations of the three other genes on the expression of the recessive lethal antimorphic Abruptex mutations of the Notch locus. The Abruptex mutations were also coupled in cis or trans with facet-glossy or split mutations of the Notch locus. In some of the experiments, the genotype of the fly was homozygous for either facet-glossy or split mutation or their wild type alleles but heterozygous for the Abruptex. Facet-glossy is located in a large intron of the locus, whereas split is located in the same exon as Abruptex. In all compounds studied, Delta suppressed the expression of Abruptex while Hairless and Enhancer of split enhanced it. The interactions of the four genes studied were allele specific, suggesting an interaction at the protein level. The comparison of the results presented in this study on the interaction of the neurogenic genes with other results on the same subject suggests that the interactions are similar in embryonic and imaginal development. Copyright © Cambridge University Press 1989 Siren Mariitta Laboratory of Genetics, Department of Biology, University of Turku, SF-20500 Turku 50, Finland Portin Petter Laboratory of Genetics, Department of Biology, University of Turku, SF-20500 Turku 50, Finland Genetical Research Cambridge University Press 54/1(1989-08), 23-26 0016-6723 54:1<23 1989 54 GRH https://doi.org/10.1017/S0016672300028330 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0016672300028330 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Siren Mariitta Laboratory of Genetics, Department of Biology, University of Turku, SF-20500 Turku 50, Finland NATIONALLICENCE 700 1- Portin Petter Laboratory of Genetics, Department of Biology, University of Turku, SF-20500 Turku 50, Finland NATIONALLICENCE 773 0- Genetical Research Cambridge University Press 54/1(1989-08), 23-26 0016-6723 54:1<23 1989 54 GRH CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge