caa a22 4500 386393508 CHVBK 20180307112128.0 cr unu---uuuuu 161130e198906 xx s 000 0 eng 10.1017/S0016672300028111 doi S0016672300028111 pii (NATIONALLICENCE)cambridge-10.1017/S0016672300028111 Mutant alleles of the meiotic locus, mei-9, differ in degree of effects on rod chromosome magnification and ring chromosome transmission in Drosophila [Elektronische Daten] Two mutant alleles of the meiotic locus, mei-9, have been examined for their effect on magnification of a rod Xbb chromosome and transmission of a ring Xbb chromosome under magnifying conditions. Our results indicate that the effects of these two mutations are allele-specific: mei-9a strongly inhibits both rod chromosome magnification and ring chromosome loss under magnifying conditions, while mei-9b has a smaller inhibitory effect on rod chromosome magnification and on the transmission of ring chromosomes under magnifying conditions. These observations can be explained by a difference in leakiness between the two alleles. Our results demonstrate that mutants defective in excision repair and repair replication inhibit ribosomal gene magnification. This suggests that a component of the excision repair pathway is involved in the process of magnification. Copyright © Cambridge University Press 1989 Komma Donald J. Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 Graves Heath Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 Endow Sharyn A. Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 Genetical Research Cambridge University Press 53/3(1989-06), 155-161 0016-6723 53:3<155 1989 53 GRH https://doi.org/10.1017/S0016672300028111 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0016672300028111 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Komma Donald J. Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 NATIONALLICENCE 700 1- Graves Heath Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 NATIONALLICENCE 700 1- Endow Sharyn A. Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710 NATIONALLICENCE 773 0- Genetical Research Cambridge University Press 53/3(1989-06), 155-161 0016-6723 53:3<155 1989 53 GRH CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge