caa a22 4500 386393524 CHVBK 20180307112128.0 cr unu---uuuuu 161130e198906 xx s 000 0 eng 10.1017/S0016672300028184 doi S0016672300028184 pii (NATIONALLICENCE)cambridge-10.1017/S0016672300028184 Age differences between distributions of genotypes among pregnant women: evidence of fertility selection [Elektronische Daten] The number of children produced by a modern woman is usually below her total reproductive capacity and is determined by circumstances other than natural selection. It is, therefore, practically impossible to detect differences in natural fertilities associated with different types (e.g. phenotypes, genotypes) of women. This does not mean, however, that natural selection at the reproductive level cannot at all be detected today. If women of a particular type have high natural fertility, this usually means that they reproduce (become pregnant) at a higher rate than women of a type with lower natural fertility. Hence, when there is a limit on the number of children, women of the first type will reach the limit at an earlier age than women of the second type. As a result, types that have a higher natural fertility should be overrepresented among pregnant women of younger ages and, consequently, underrepresented among older ones, as compared to types with a lower natural fertility. Based on this notion, a model of age-related differences between distributions of types among pregnant women is suggested. The model is applied to data on MNSs-blood group and PGM1 (phosphoglucomutase) types in a sample of pregnant women and an evidence of natural selection at the reproduction level associated with these genetic markers is obtained. Copyright © Cambridge University Press 1989 Gimelfarb A. Department of Ecology and Evolution, The University of Chicago, Chicago, IL 60637, USA Bottini E. Division of Biometry and Human Development, School of Medicine, 2nd University of Rome, Rome, Italy Genetical Research Cambridge University Press 53/3(1989-06), 207-214 0016-6723 53:3<207 1989 53 GRH https://doi.org/10.1017/S0016672300028184 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0016672300028184 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gimelfarb A. Department of Ecology and Evolution, The University of Chicago, Chicago, IL 60637, USA NATIONALLICENCE 700 1- Bottini E. Division of Biometry and Human Development, School of Medicine, 2nd University of Rome, Rome, Italy NATIONALLICENCE 773 0- Genetical Research Cambridge University Press 53/3(1989-06), 207-214 0016-6723 53:3<207 1989 53 GRH CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge