caa a22 4500 386399484 CHVBK 20180307112153.0 cr unu---uuuuu 161130e198902 xx s 000 0 eng 10.1017/S0031182000059722 doi S0031182000059722 pii (NATIONALLICENCE)cambridge-10.1017/S0031182000059722 Studies on motility in vitro of an ectoparasitic monogenean, Diclidophora merlangi [Elektronische Daten] An isometric transducer system has been used to record spontaneous motor activity in Diclidophora merlangi in vitro. Motility took the form of either continuous irregular contractions or bursts of activity with intermittent quiescent periods. Maximal activity was recorded from specimens at 5-8 °C in artificial sea water (ASW). Decerebration induced a period of enhanced motility which subsided within 1 h. Water turbulence elicited large, rapid contractions of the longitudinal body musculature which did not habituate or fatigue. Induced water turbulence at frequencies higher than 3/min inhibited spontaneous movements, resulting in a progressive reduction in contraction amplitude and, eventually (30/min), the abolition of any response to water movement. The neurotoxin tetrodotoxin failed to modify worm activity. Excitatory responses from both intact worms and strip preparations were obtained with 5-hydroxytryptamine, dopamine and noradrenaline, but aminergic antagonists failed to block their effects. Atropine stimulated contractility, whereas the effects of acetylcholine or carbachol were inconsistent. Nicotine increased muscle tone but the effect was unaltered by atropine, mecamylamine or d-tubocurarine. Muscarine, hemicholinium, neostigmine and eserine were without apparent effect. Copyright © Cambridge University Press 1989 Diclidophora merlangi nationallicence monogenean nationallicence motility nationallicence aminergic drugs nationallicence cholinergic drugs nationallicence Maule A. G. Department of Biology, The Queen's University, Belfast BT7 1NN Halton D. W. Department of Biology, The Queen's University, Belfast BT7 1NN Allen J. M. Biomedical Sciences Research Centre, University of Ulster at Jordanstown B37 0QB Fairweather I. Department of Biology, The Queen's University, Belfast BT7 1NN Parasitology Cambridge University Press 98/1(1989-02), 85-93 0031-1820 98:1<85 1989 98 PAR https://doi.org/10.1017/S0031182000059722 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0031182000059722 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Maule A. G. Department of Biology, The Queen's University, Belfast BT7 1NN NATIONALLICENCE 700 1- Halton D. W. Department of Biology, The Queen's University, Belfast BT7 1NN NATIONALLICENCE 700 1- Allen J. M. Biomedical Sciences Research Centre, University of Ulster at Jordanstown B37 0QB NATIONALLICENCE 700 1- Fairweather I. Department of Biology, The Queen's University, Belfast BT7 1NN NATIONALLICENCE 773 0- Parasitology Cambridge University Press 98/1(1989-02), 85-93 0031-1820 98:1<85 1989 98 PAR CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge