caa a22 4500 386399557 CHVBK 20180307112153.0 cr unu---uuuuu 161130e198901 xx s 000 0 eng 10.1017/S0031182000072218 doi S0031182000072218 pii (NATIONALLICENCE)cambridge-10.1017/S0031182000072218 Roitt I. M. Department of Immunology, University College and Middlesex School of Medicine, London WI Basic concepts and new aspects of vaccine development [Elektronische Daten] [I. M. Roitt] I wish to thank the Society for inviting me to give the Introductory Talk in this Symposium. It is going to centre around what might be called ‘epitope specific' immunization and I want to draw your attention to a number of factors which will be bound to affect any new approach to the development of vaccines. To begin with, it is now clear that complex antigens, such as those associated with parasites, present many different epitopes to the immune system. These epitopes are ‘seen' by different cell types using different receptors and epitope recognition can activate a number of different effector systems. Copyright © Cambridge University Press 1989 vaccine development nationallicence epitope recognition nationallicence protein engineering nationallicence B cell responses nationallicence T cell responses nationallicence Parasitology Cambridge University Press 98/S1(1989-01), S7-S18 0031-1820 98:S1<S7 1989 98 PAR https://doi.org/10.1017/S0031182000072218 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0031182000072218 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Roitt I. M. Department of Immunology, University College and Middlesex School of Medicine, London WI NATIONALLICENCE 773 0- Parasitology Cambridge University Press 98/S1(1989-01), S7-S18 0031-1820 98:S1<S7 1989 98 PAR CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge