caa a22 4500 386399794 CHVBK 20180307112154.0 cr unu---uuuuu 161130e198910 xx s 000 0 eng 10.1017/S0031182000058625 doi S0031182000058625 pii (NATIONALLICENCE)cambridge-10.1017/S0031182000058625 Chapman H. D. Institute for Animal Health, Houghton Laboratory, Houghton, Huntingdon, Cambridgeshire PE17 2DA Eimeria tenella, E. acervulina and E. maxima: studies on the development of resistance to diclazuril and other anticoccidial drugs in the chicken [Elektronische Daten] [H. D. Chapman] Resistance to diclazuril was induced by 10 passages of the Houghton strains of Eimeria acervulina and E. tenella in chickens given progressively greater concentrations of the drug. This resistance was, however, not complete since the drug retained some efficacy against the drug-passaged lines. Attempts to passage the Houghton strain of E. maxima in birds medicated with concentrations of diclazuril greater than 0·016 parts per million (ppm) were unsuccessful and after 10 passages at this concentration resistance had not developed. Resistance to methyl benzoquate developed after 6 passages of E. tenella in medicated chickens but resistance to amprolium was only partial after 10 passages. The pathogenicity of diclazuril- and amprolium-resistant lines of E. tenella was lower than that of the parental line. Diclazuril was effective against lines of E. tenella resistant to amprolium, arprinocid, clopidol, dinitolmide, halofuginone, methyl benzoquate, monensin and robenidine. Copyright © Cambridge University Press 1989 Eimeria spp nationallicence resistance nationallicence diclazuril nationallicence anticoccidial drugs nationallicence Parasitology Cambridge University Press 99/2(1989-10), 189-192 0031-1820 99:2<189 1989 99 PAR https://doi.org/10.1017/S0031182000058625 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0031182000058625 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Chapman H. D. Institute for Animal Health, Houghton Laboratory, Houghton, Huntingdon, Cambridgeshire PE17 2DA NATIONALLICENCE 773 0- Parasitology Cambridge University Press 99/2(1989-10), 189-192 0031-1820 99:2<189 1989 99 PAR CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge