caa a22 4500 386399964 CHVBK 20180307112155.0 cr unu---uuuuu 161130e198910 xx s 000 0 eng 10.1017/S0031182000058698 doi S0031182000058698 pii (NATIONALLICENCE)cambridge-10.1017/S0031182000058698 The effects of cholinergic and serotoninergic drugs on motility in vitro of Haplometra cylindracea (Trematoda: Digenea) [Elektronische Daten] The spontaneous activity of the somatic muscle of the amphibian lung fluke, Haplometra cylindracea has been recorded in vitro, using an isometric force transducer system. Normal movement consisted of a continuous series of regular contractions which were maintained for over 4 h. Acetylcholine (ACh) inhibited motility and at a concentration of 1 χ 10-3 M induced a flaccid paralysis. A similar response occurred with the cholinomimetic drugs, carbachol and nicotine, although in these instances the inhibition was less easily reversed by washing with frog Ringer. The inhibitory effect of ACh was blocked by d-tubocurarine but not by atropine. Copyright © Cambridge University Press 1989 Haplometra cylindracea nationallicence trematode nationallicence digenetic nationallicence motility in vitro nationallicence neuromuscular system nationallicence cholinergic drugs nationallicence aminergic drugs nationallicence McKay D. M. Department of Biology, The Queen's University, Belfast BT7 1NN, UK Halton D. W. Department of Biology, The Queen's University, Belfast BT7 1NN, UK Allen J. M. Biomedical Sciences Research Centre, University of Ulster at Jordanstown, Co. Antrim BT37 0QB, UK Fairweather I. Department of Biology, The Queen's University, Belfast BT7 1NN, UK Parasitology Cambridge University Press 99/2(1989-10), 241-252 0031-1820 99:2<241 1989 99 PAR https://doi.org/10.1017/S0031182000058698 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0031182000058698 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- McKay D. M. Department of Biology, The Queen's University, Belfast BT7 1NN, UK NATIONALLICENCE 700 1- Halton D. W. Department of Biology, The Queen's University, Belfast BT7 1NN, UK NATIONALLICENCE 700 1- Allen J. M. Biomedical Sciences Research Centre, University of Ulster at Jordanstown, Co. Antrim BT37 0QB, UK NATIONALLICENCE 700 1- Fairweather I. Department of Biology, The Queen's University, Belfast BT7 1NN, UK NATIONALLICENCE 773 0- Parasitology Cambridge University Press 99/2(1989-10), 241-252 0031-1820 99:2<241 1989 99 PAR CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge