caa a22 4500 388032898 CHVBK 20180307124957.0 cr unu---uuuuu 161130e199812 xx s 000 0 eng 10.1086/647763 doi S0195941700092122 pii (NATIONALLICENCE)cambridge-10.1086/647763 Tuberculosis, Hepatitis B, Rubella, Rubeola, and Varicella Infection and Immunity Among Medical School Employees [Elektronische Daten] Abstract Objective: To assess baseline health status of a medical school employee population and to assess this population's acceptance of vaccination and other interventions to reduce risk of disease transmission. Design: A retrospective review of an employee health records database for a 4-year period. Setting: A large, urban university hospital. Participants: 5,007 employees screened by employee health for immunity to vaccine-preventable illnesses and tuberculosis. Results: 9.4% of the employees had positive tuberculin skin tests, with a conversion rate of 6.4% for those who had negative tests within the previous 2 years. Two individuals were identified who had active pulmonary tuberculosis. Fewer than 10% of the individuals for whom isoniazid chemoprophylaxis was recommended completed the 6 months of therapy. Most clinical employees (96.1%) did not have a history of prior hepatitis B virus (HBV) infection or immunization, but 77% of them subsequently completed the vaccination series. Most employees with a negative history for infection with or immunization against rubella, rubeola, and varicella had serological evidence of immunity (90.2%, 97.9%, and 87.2%, respectively). Conclusions: Review of aggregate employee health databases may assist individuals who must establish strategies for prevention of occupational illness and disease transmission in this specialized setting. While many employees at risk for HBV complete the vaccination series, strategies for improving this rate could be helpful. Substantial work is needed to analyze reasons why so few individuals for whom isoniazid chemoprophylaxis is recommended complete the therapy, and strategies tailored to the impediments identified should be implemented. Copyright © The Society for Healthcare Epidemiology of America 1998 L'Ecuyer Paul B. Division of Infectious Diseases Miller Marilyn Division of Infectious Diseases Winters Karen Division of Infectious Diseases Fraser Victoria J. Division of Infectious Diseases Infection Control & Hospital Epidemiology Cambridge University Press 19/12(1998-12), 915-917 0899-823X 19:12<915 1998 19 ICE https://doi.org/10.1086/647763 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1086/647763 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- L'Ecuyer Paul B. Division of Infectious Diseases NATIONALLICENCE 700 1- Miller Marilyn Division of Infectious Diseases NATIONALLICENCE 700 1- Winters Karen Division of Infectious Diseases NATIONALLICENCE 700 1- Fraser Victoria J. Division of Infectious Diseases NATIONALLICENCE 773 0- Infection Control & Hospital Epidemiology Cambridge University Press 19/12(1998-12), 915-917 0899-823X 19:12<915 1998 19 ICE CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge