caa a22 4500 388033509 CHVBK 20180307124958.0 cr unu---uuuuu 161130e199803 xx s 000 0 eng 10.2307/30143438 doi S0195941700087130 pii (NATIONALLICENCE)cambridge-10.2307/30143438 Carriage of Methicillin-Resistant Staphylococcus Aureus at Hospital Admission [Elektronische Daten] Abstract Objectives: To measure the prevalence of, and to establish predictors for, the nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) at hospital admission. To evaluate mannitol-salt agar with oxacillin for the simultaneous detection and identification of MRSA from nasal swabs. Design: Three-month prospective case-control survey, with data collected from interviews and computerized databases. The criterion standard for MRSA detection was culture on Mueller-Hinton agar with oxacillin 6 μg/mL (National Committee for Clinical Laboratory Standards method). Setting: 320-bed tertiary-care hospital. Patients: 387 patients screened within 24 hours after admission, including 10 MRSA carriers (cases), 291 patients with no S aureus, and 86 patients with methicillin-susceptible S aureus. Results: The prevalence of MRSA nasal carriage was 2.6%, whereas the prevalence of carriage was 3.1% when both nasal and wound cultures were performed. The significant predictors of carriage were a prior detection of MRSA, open wounds, diabetes mellitus, treatments by injection, prior nursing home stays, visits at home by a nurse, and prior antibiotic treatments. Cases had stayed for longer periods in hospitals and had received longer antibiotic treatments within a year. Eighty patients (including the 10 cases) had diabetes, had been exposed to healthcare facilities within a year, and had antibiotics within 6 months. The sensitivity and negative predictive value of nasal swabs on mannitol-salt agar with oxacillin were 60% and 71%, respectively. Conclusion: MRSA carriage on admission to the hospital may be an increasing and underestimated problem. Further studies are needed to develop and validate a sensitive and specific prediction rule. Copyright © The Society for Healthcare Epidemiology of America 1998 Troillet Nicolas Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Carmeli Yehuda Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Samore Matthew H. Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Dakos Joanna Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Eichelberger Karen Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts DeGirolami Paola C. Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Karchmer Adolf W. Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Infection Control & Hospital Epidemiology Cambridge University Press 19/3(1998-03), 180-185 0899-823X 19:3<180 1998 19 ICE https://doi.org/10.2307/30143438 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.2307/30143438 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Troillet Nicolas Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- Carmeli Yehuda Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- Samore Matthew H. Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- Dakos Joanna Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- Eichelberger Karen Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- DeGirolami Paola C. Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 700 1- Karchmer Adolf W. Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts NATIONALLICENCE 773 0- Infection Control & Hospital Epidemiology Cambridge University Press 19/3(1998-03), 180-185 0899-823X 19:3<180 1998 19 ICE CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge