caa a22 4500 388033525 CHVBK 20180307124958.0 cr unu---uuuuu 161130e199803 xx s 000 0 eng 10.1086/647788 doi S0195941700087087 pii (NATIONALLICENCE)cambridge-10.1086/647788 A Viral Gastroenteritis Outbreak Associated with Person-to-Person Spread Among Hospital Staff [Elektronische Daten] Abstract Objective: To identify the etiologic agent and risk factors associated with a hospital ward outbreak of gastroenteritis. Setting: A regional referral hospital in upstate South Carolina. Methods: We reviewed patient charts, surveyed staff, and tested stool from acutely ill persons. A case was defined as diarrhea and vomiting in a staff member or patient from January 5 to 13, 1996. Results: The initial case occurred on January 5 in a staff nurse who subsequently was hospitalized on the ward and visited by many staff colleagues. The staff were at a significantly greater risk for gastroenteritis than were patients (28/89 [31%] vs 10/91 [11%]; relative risk [RR], 2.9; 95% confidence interval [CI95], 1.5-5.5). All 10 case-patients had been exposed to case-nurses (assigned nurses who were primary caretakers), and eight had documented exposure to case-nurses 1 to 2 days before their illness. Patients exposed to case-nurses had a significantly increased risk of illness (8/57 [14%] vs 0/32; RR, >4.5; CI95, undefined). Neither staff nor patients had significantly increased risk from food, water, ice, or exposure to case-patients. Electron microscopy identified small round-structured viruses (SRSVs) in nine of nine stool samples. Conclusion: This nosocomial outbreak of gastroenteritis was likely caused by SRSVs introduced by a staff member and spread via person-to-person transmission from and among staff. The potential for spread of SRSV-associated gastroenteritis from and among staff should be considered in developing strategies to prevent similar outbreaks in hospital settings Copyright © The Society for Healthcare Epidemiology of America 1998 Cáceres Victor M. Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia Kim David K. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia Bresee Joseph S. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia Horan John Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia Noel Jacqueline S. South Carolina Department of Health and Human Environmental Control, Columbia, South Carolina Ando Tamie Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia Steed Connie J. Greenville Hospital System, Greenville, South Carolina Weems J. John Greenville Hospital System, Greenville, South Carolina Monroe Stephan S. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia Gibson James J. Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia Infection Control & Hospital Epidemiology Cambridge University Press 19/3(1998-03), 162-167 0899-823X 19:3<162 1998 19 ICE https://doi.org/10.1086/647788 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1086/647788 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cáceres Victor M. Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Kim David K. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Bresee Joseph S. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Horan John Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Noel Jacqueline S. South Carolina Department of Health and Human Environmental Control, Columbia, South Carolina NATIONALLICENCE 700 1- Ando Tamie Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Steed Connie J. Greenville Hospital System, Greenville, South Carolina NATIONALLICENCE 700 1- Weems J. John Greenville Hospital System, Greenville, South Carolina NATIONALLICENCE 700 1- Monroe Stephan S. Division of Viral and Rickettsial Diseases, the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 700 1- Gibson James J. Division of Field Epidemiology, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia NATIONALLICENCE 773 0- Infection Control & Hospital Epidemiology Cambridge University Press 19/3(1998-03), 162-167 0899-823X 19:3<162 1998 19 ICE CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge