caa a22 4500 388035005 CHVBK 20180307125001.0 cr unu---uuuuu 161130e199809 xx s 000 0 eng S0195941700005889 doi S0195941700005889 pii (NATIONALLICENCE)cambridge-S0195941700005889 Experience With Two Validation Methods in a Prevalence Survey on Nosocomial Infections [Elektronische Daten] Abstract Objective: To determine whether an investigator effect remained on the first German study on the prevalence of nosocomial infections Nosokomiale Infektionen in Deutschland Erfassung und Prävention (NIDEP), despite extensive validation efforts. Design: Two validation methods were applied: bedside validation and validation by case studies. In both cases, the results of the four investigators were compared with the diagnosis of gold standard observers. Setting: Validation measures were applied before, intermittently, during, and at the end of the surveillance period in 72 acute-care hospitals with 14,966 patients. Results: The overall sensitivity in the bedside-validation periods was 89.0%; the overall specificity was 99.5%. For validation by case studies, overall sensitivity was 95.6%, and overall specificity was 92.8%. At the end of the surveillance, a remarkable investigator effect was found. Conclusion: Despite validation results that were assessed as satisfactory, based on available literature, an investigator effect was observed. This underlines the need for data validation and the formulation of recommendations for data validation. Clarification of the Centers for Disease Control and Prevention criteria for pneumonia and primary bloodstream infection and the inclusion of some diagnostic test results may reduce or prevent an investigator effect in future studies. Copyright © The Society for Healthcare Epidemiology of America 1998 Gastmeier Petra Institute of Hygiene, Free University Berlin, Berlin, Germany Kampf Günter Institute of Hygiene, Free University Berlin, Berlin, Germany Hauer Thomas Institute of Environmental Medicine and Hospital Epidemiology, Albert-Ludwigs-University Freiburg, Freiburg, Germany Schlingmann Jürgen Institute for Medical Biometry and Medical Informatics, Albert-Ludwigs-University Freiburg, Freiburg, Germany Schumacher Martin Institute for Medical Biometry and Medical Informatics, Albert-Ludwigs-University Freiburg, Freiburg, Germany Daschner Franz Institute of Environmental Medicine and Hospital Epidemiology, Albert-Ludwigs-University Freiburg, Freiburg, Germany Rüden Henning Institute of Hygiene, Free University Berlin, Berlin, Germany Infection Control & Hospital Epidemiology Cambridge University Press 19/9(1998-09), 668-673 0899-823X 19:9<668 1998 19 ICE https://doi.org/S0195941700005889 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/S0195941700005889 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gastmeier Petra Institute of Hygiene, Free University Berlin, Berlin, Germany NATIONALLICENCE 700 1- Kampf Günter Institute of Hygiene, Free University Berlin, Berlin, Germany NATIONALLICENCE 700 1- Hauer Thomas Institute of Environmental Medicine and Hospital Epidemiology, Albert-Ludwigs-University Freiburg, Freiburg, Germany NATIONALLICENCE 700 1- Schlingmann Jürgen Institute for Medical Biometry and Medical Informatics, Albert-Ludwigs-University Freiburg, Freiburg, Germany NATIONALLICENCE 700 1- Schumacher Martin Institute for Medical Biometry and Medical Informatics, Albert-Ludwigs-University Freiburg, Freiburg, Germany NATIONALLICENCE 700 1- Daschner Franz Institute of Environmental Medicine and Hospital Epidemiology, Albert-Ludwigs-University Freiburg, Freiburg, Germany NATIONALLICENCE 700 1- Rüden Henning Institute of Hygiene, Free University Berlin, Berlin, Germany NATIONALLICENCE 773 0- Infection Control & Hospital Epidemiology Cambridge University Press 19/9(1998-09), 668-673 0899-823X 19:9<668 1998 19 ICE CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge