caa a22 4500 388058854 CHVBK 20180307125114.0 cr unu---uuuuu 161130e19980801xx s 000 0 eng 10.1375/twin.1.4.176 doi S1369052300000416 pii (NATIONALLICENCE)cambridge-10.1375/twin.1.4.176 Effects of lifestyle, personality, symptoms of anxiety and depression, and genetic predisposition on subjective sleep disturbance and sleep pattern [Elektronische Daten] The effects on sleep pattern (‘short-sleep' versus ‘long-sleep') and subjective sleep disturbance of genotype, personality, symptoms of anxiety and depression, and lifestyle, were examined using survey data on a clinically unselected sample of adult Australian twin pairs, aged 17-88 years. When the effects of genotype, personality and symptoms were ignored, lifestyle variables appeared to account for roughly 4% of the variance in sleep disturbance, and 9% of the variance in sleep pattern. Significant genetic effects on sleep disturbance and sleep pattern were found, which were only partly explained by the effects of personality and symptoms of anxiety and depression. Much of the association between sleep disturbance and lifestyle appeared to be explained by separate effects of personality and symptoms of anxiety and depression on sleep and lifestyle (‘genotype - risk-factor correlation'). There was little evidence for genetically determined differences in sensitivity to the lifestyle variables (‘genotype × risk-factor interaction'). Copyright © Cambridge University Press 1998 sleep nationallicence genetics nationallicence twins nationallicence personality nationallicence Heath Andrew C. Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri. Eaves Lindon J. Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia, Richmond, Virginia, USA. Kirk Katherine M. Queensland Institute of Medical Research, Brisbane, Australia. Martin Nicholas G. Queensland Institute of Medical Research, Brisbane, Australia. nickM@qimr.edu.au Twin Research Cambridge University Press 1/4(1998-08-01), 176-188 1369-0523 1:4<176 1998 1 THG https://doi.org/10.1375/twin.1.4.176 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1375/twin.1.4.176 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heath Andrew C. Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri NATIONALLICENCE 700 1- Eaves Lindon J. Institute of Psychiatric and Behavioral Genetics, Medical College of Virginia, Richmond, Virginia, USA NATIONALLICENCE 700 1- Kirk Katherine M. Queensland Institute of Medical Research, Brisbane, Australia NATIONALLICENCE 700 1- Martin Nicholas G. Queensland Institute of Medical Research, Brisbane, Australia. nickM@qimr.edu.au NATIONALLICENCE 773 0- Twin Research Cambridge University Press 1/4(1998-08-01), 176-188 1369-0523 1:4<176 1998 1 THG CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge