caa a22 4500 388058889 CHVBK 20180307125115.0 cr unu---uuuuu 161130e19980801xx s 000 0 eng 10.1375/twin.1.4.189 doi S1369052300000428 pii (NATIONALLICENCE)cambridge-10.1375/twin.1.4.189 Time trends in twin perinatal mortality in northern England, 1982-94 [Elektronische Daten] The dynamics of perinatal mortality rates (PNMR) and causes of death in twin pregnancies over 13 years in the Northern Region of the National Health Service in England is described. All twin perinatal deaths occurring between 1982-1994 were identified from the Northern Region Perinatal Mortality Survey. The twinning rate increased from 9.9 per 1000 maternities in 1982 to 12.0 in 1994. There was a total of 10734 twin pregnancies and of these 421 resulted in 530 perinatal deaths. The perinatal mortality rate in twins significantly decreased over time (1982-87, 55.4 per 1000; 1988-94, 44.4 per 1000; P = 0.01). The PNMR was significantly higher for twins from like-sexed than from unlike-sexed pairs (53.5 and 34.4 per 1000 respectively, P < 0.001). Despite no improvement in birthweight distribution in the twin population, birthweight-specific perinatal mortality rates for both like and unlike-sexed twins decreased for each birthweight category in 1988-94 compared with 1982-87. Twins with very low birthweight ( < 1500 g) comprised 69%, and preterm twins ( < 37 completed weeks of gestation) 74.9% of all twin perinatal deaths. The major immediate cause of early neonatal death was pulmonary immaturity (63%); antepartum anoxia caused 76.9% of antenatal deaths. Unexplained preterm labour and intrauterine death were the leading obstetric factors underlying death in twins. Despite a decrease over the 13 years, the perinatal mortality rate in twins in the Northern Region remains high. Continued monitoring of trends in twinning and mortality rates is needed to inform health care planning. Copyright © Cambridge University Press 1998 twinning nationallicence birthweight-specific perinatal mortality nationallicence monozygotic and dizygotic twins nationallicence prematurity nationallicence low birthweight nationallicence Glinianaia Svetlana V. Department of Epidemiology & Public Health, The Medical School, University of Newcastle. Svetlana.Glinianaia@ncl.ac.uk Rankin Judith Department of Epidemiology & Public Health, The Medical School, University of Newcastle. Renwick Marjorie Northern Region Perinatal Mortality Survey, Maternity Survey Office, Newcastle upon Tyne, UK. Twin Research Cambridge University Press 1/4(1998-08-01), 189-195 1369-0523 1:4<189 1998 1 THG https://doi.org/10.1375/twin.1.4.189 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1375/twin.1.4.189 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Glinianaia Svetlana V. Department of Epidemiology & Public Health, The Medical School, University of Newcastle. Svetlana.Glinianaia@ncl.ac.uk NATIONALLICENCE 700 1- Rankin Judith Department of Epidemiology & Public Health, The Medical School, University of Newcastle NATIONALLICENCE 700 1- Renwick Marjorie Northern Region Perinatal Mortality Survey, Maternity Survey Office, Newcastle upon Tyne, UK NATIONALLICENCE 773 0- Twin Research Cambridge University Press 1/4(1998-08-01), 189-195 1369-0523 1:4<189 1998 1 THG CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge