caa a22 4500 388059273 CHVBK 20180307125116.0 cr unu---uuuuu 161130e199806 xx s 000 0 eng 10.1079/PHN19980015 doi S1368980098000160 pii (NATIONALLICENCE)cambridge-10.1079/PHN19980015 A longitudinal study of iron status in children at 12, 24 and 36 months [Elektronische Daten] Abstract Objectives: To assess iron status in a sample of clinically well, Caucasian children and explore the complex factors which contribute to iron deficiency during infancy. Design: Infants recruited at birth and followed longitudinally at 1, 2, 3, 4, 5, 6, 9, 12, 24 and 36 months; feeding practices and socioeconomic data recorded. Iron status assessed using venous blood at 12, 24 and 36 months. Setting: Baseline data recorded in the maternity unit. Follow-up visits took place in the infants' homes and blood sampling in a paediatric hospital. Subjects: Subjects comprised a mixed socioeconomic group of healthy children (n=121). Blood samples taken from 85, 72 and 67% at 12, 24 and 36 months, respectively. Results: Prevalence of anaemia (Hb < 110 gl−1) in the longitudinal sample (n=76) increased from 2.6% at age 12 months to 9.2% at 24 months, and at age 36 months (n=70) was 8%. The most significant finding was that at age 12 months, cows' milk consumption was negatively associated with iron status. Other variables also had an influence. At both 24 and 36 months the most significant predictor of iron status was earlier iron status. Conclusions: Infants born to anaemic mothers or mothers who smoke and infants who consume cows' milk during infancy are at increased risk of developing anaemia. Breast milk is the ideal, but for the infant who is not breast fed an iron fortified formula should be used. Advice to mothers should focus on the importance of introducing nutrient dense complementary foods, such as meat, which contains readily absorbable iron. Copyright © The Nutrition Society 1998 Anaemia nationallicence Infant feeding nationallicence cows' milk nationallicence Freeman VE Division of Nutritional Sciences, Department of Clinical Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland Mulder J. Department of Medical Statistics, Catholic University of Nijmegen, Nijmegen, The Netherlands van't Hof MA Department of Medical Statistics, Catholic University of Nijmegen, Nijmegen, The Netherlands Hoey HMV Department of Paediatrics, the University of Dublin, Trinity College, Dublin 2, Ireland Gibney MJ Division of Nutritional Sciences, Department of Clinical Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland Public Health Nutrition Cambridge University Press 1/2(1998-06), 93-100 1368-9800 1:2<93 1998 1 PHN https://doi.org/10.1079/PHN19980015 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/PHN19980015 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Freeman VE Division of Nutritional Sciences, Department of Clinical Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland NATIONALLICENCE 700 1- Mulder J. Department of Medical Statistics, Catholic University of Nijmegen, Nijmegen, The Netherlands NATIONALLICENCE 700 1- van't Hof MA Department of Medical Statistics, Catholic University of Nijmegen, Nijmegen, The Netherlands NATIONALLICENCE 700 1- Hoey HMV Department of Paediatrics, the University of Dublin, Trinity College, Dublin 2, Ireland NATIONALLICENCE 700 1- Gibney MJ Division of Nutritional Sciences, Department of Clinical Medicine, Trinity Centre for Health Sciences, St James's Hospital, Dublin 8, Ireland NATIONALLICENCE 773 0- Public Health Nutrition Cambridge University Press 1/2(1998-06), 93-100 1368-9800 1:2<93 1998 1 PHN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge