caa a22 4500 388061812 CHVBK 20180307125122.0 cr unu---uuuuu 161130e199802 xx s 000 0 eng 10.1017/S0007114598001068 doi S0007114598001068 pii (NATIONALLICENCE)cambridge-10.1017/S0007114598001068 Replacement of linoleic acid with α-linolenic acid does not alter blood lipids in normolipidaemic men [Elektronische Daten] The effect of partial dietary replacement of linoleic acid (18:2n-6; linoleic acid-rich diet) with α-linolenic acid (18:3n-3; α-linolenic acid-rich diet) on plasma lipids was investigated in twenty-nine healthy young men. After a 2-week stabilization period subjects were randomly assigned to either the α-linolenic acid-rich diet group (n 15), receiving a mean of 10.1 g of α-linolenic acid and 12.1 g of linoleic acid/d, or the linoleic acid-rich diet group (n 14), receiving a mean of 1.0 g of α-linolenic acid and 21.0 g of linoleic acid/d, for a 6-week test period. Blood samples were taken at the commencement of the stabilization period and at the start (week 0), midpoint (week 3) and endpoint (week 6) of the test period and plasma lipids analysed. The changes occurring on the linoleic acid-rich diet and α-linolenic acid-rich diet were compared but no significant differences in the changes in plasma total cholesterol, LDL-cholesterol, HDL-cholesterol, the subfractions HDL2 and HDL3 or triacylglycerols were found. These results indicate that dietary replacement of linoleic acid with α-linolenic acid in the diet of healthy male subjects offers similar cardioprotective benefits with respect to lipid metabolism. Copyright © The Nutrition Society 1998 Linolenic acid nationallicence Linoleic acid nationallicence Blood lipids nationallicence Linseed oil nationallicence Pang D. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia Allman-Farinelli M. A. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia Wong T. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia Barnes R. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia Kingham K. M. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia British Journal of Nutrition Cambridge University Press 80/2(1998-02), 163-167 0007-1145 80:2<163 1998 80 BJN https://doi.org/10.1017/S0007114598001068 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0007114598001068 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pang D. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia NATIONALLICENCE 700 1- Allman-Farinelli M. A. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia NATIONALLICENCE 700 1- Wong T. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia NATIONALLICENCE 700 1- Barnes R. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia NATIONALLICENCE 700 1- Kingham K. M. Human Nutrition Unit, Department of Biochemistry, University of Sydney, NSW 2006, Australia NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 80/2(1998-02), 163-167 0007-1145 80:2<163 1998 80 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge