caa a22 4500 388061847 CHVBK 20180307125123.0 cr unu---uuuuu 161130e199802 xx s 000 0 eng 10.1017/S0007114598001081 doi S0007114598001081 pii (NATIONALLICENCE)cambridge-10.1017/S0007114598001081 Effect of dietary phytic acid on zinc absorption in the healthy elderly, as assessed by serum concentration curve tests [Elektronische Daten] Zn absorption was investigated in healthy elderly subjects aged 71-78 years and in young subjects aged 23-43 years using serum concentration curve (SCC) tests. Both groups had similar Zn and protein status. The increase in serum Zn was monitored for 180 min after ingestion of 200ml of soya milk enriched with 50mg of Zn. Three levels of phytic acid were used: 0g/200ml (totally dephytinized soya milk), 0.13 g/200ml (half dephytinized), and 0.26 g/200ml (natural phytic acid content). In a first study the effect of 0 v. 0.26 g/200 ml phytic acid was compared in 10 elderly and 10 young subjects, each subject receiving both treatments. In a second study soya milks with 0 and 0.13 g/200ml were tested in nine elderly and ten young subjects, again receiving both treatments. Mean areas under the curve of the SCC tests conducted with the 0 g/200 ml soya milk were found to be the same in both studies. Phytic acid strongly depressed Zn absorption in both studies (P ≤ 0.05), but to a greater extent at the 0.26 g/200ml level. No difference was found between the groups of young and elderly subjects. Therefore, no significant effect of aging on Zn absorption, as evaluated by the SCC test, or on the inhibitory effect of phytic acid was detected. Copyright © The Nutrition Society 1998 Zinc absorption nationallicence Elderly nationallicence Phytic Acid nationallicence Couzy François Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland Mansourian Robert Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland Labate Arielle Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland Guinchard Sylvie Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland Montagne Dirk H. Nestlé Research & Development Centre, Sonnrainstrasse 19, PO Box 12, CH-3510 Konolfingen 1, Switzerland Dirren Henri Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland British Journal of Nutrition Cambridge University Press 80/2(1998-02), 177-182 0007-1145 80:2<177 1998 80 BJN https://doi.org/10.1017/S0007114598001081 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0007114598001081 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Couzy François Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland NATIONALLICENCE 700 1- Mansourian Robert Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland NATIONALLICENCE 700 1- Labate Arielle Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland NATIONALLICENCE 700 1- Guinchard Sylvie Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland NATIONALLICENCE 700 1- Montagne Dirk H. Nestlé Research & Development Centre, Sonnrainstrasse 19, PO Box 12, CH-3510 Konolfingen 1, Switzerland NATIONALLICENCE 700 1- Dirren Henri Nestlé Research Centre - NESTEC Ltd., PO Box 44, CH-1000 Lausanne 26, Switzerland NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 80/2(1998-02), 177-182 0007-1145 80:2<177 1998 80 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge