caa a22 4500 38806210X CHVBK 20180307125124.0 cr unu---uuuuu 161130e199803 xx s 000 0 eng 10.1079/BJN19980043 doi S0007114598000440 pii (NATIONALLICENCE)cambridge-10.1079/BJN19980043 Is zinc a limiting nutrient in the diets of rural pregnant Malawian women? [Elektronische Daten] Pregnant women consuming plant-based diets are at risk of Zn deficiency; Zn requirements for fetal growth and maternal tissue accretion are high. Therefore we have studied, at 24 and 33 weeks gestation, the Zn status of eighty-seven pregnant rural Malawian women (mean age 22·7 years) who consume maize-based diets, using anthropometry, dietary intake data, plasma and hair Zn concentrations, and infection status via serum C-reactive protein, leucocyte count, and malaria blood smear. Of the women, 12% were stunted (height-for-age Z score < -2 SD) and 20% lost weight over the 9-week period; weight gain averaged 0·13 kg/week. Mean plasma Zn concentration declined significantly from 24 to 33 weeks (7·9 (SD 2·2) v. 6·6 (SD 2·0) μmol/l; P < 0·0003). Both plasma and hair Zn values were very low; nearly 50% of the women had both plasma and hair Zn values below acceptable cut-off values. No significant differences in biochemical Zn indices existed between those who tested positive and negative for infection. Cereals (mainly maize) provided more than two-thirds of mean energy intake compared with less than 5% from flesh foods. As a result about 60% of the subjects had dietary phytate: Zn molar ratios greater than 15, and more than 35% had inadequate Zn intakes based on probability estimates and WHO basal requirements. Biochemical evidence of Zn deficiency was attributed in part to low intakes of poorly available Zn. The anthropometric, biochemical, and dietary data together indicate that Zn deficiency may be a factor limiting pregnancy outcome in rural Malawian women. Copyright © The Nutrition Society 1998 Zinc nationallicence Pregnancy nationallicence Malawi nationallicence Huddle Janet-Marie Division of Applied Human Nutrition, University of Guelph, Guelph, Ontario N1G 2W1, Canada Gibson Rosalind S. Department of Human Nutrition, University of Otago, PO Box 56, Dunedin, New Zealand Cullinan Timothy R. Department of Community Health, College of Medicine, University of Malawi, Blantyre, Malawi British Journal of Nutrition Cambridge University Press 79/3(1998-03), 257-265 0007-1145 79:3<257 1998 79 BJN https://doi.org/10.1079/BJN19980043 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19980043 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Huddle Janet-Marie Division of Applied Human Nutrition, University of Guelph, Guelph, Ontario N1G 2W1, Canada NATIONALLICENCE 700 1- Gibson Rosalind S. Department of Human Nutrition, University of Otago, PO Box 56, Dunedin, New Zealand NATIONALLICENCE 700 1- Cullinan Timothy R. Department of Community Health, College of Medicine, University of Malawi, Blantyre, Malawi NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 79/3(1998-03), 257-265 0007-1145 79:3<257 1998 79 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge