caa a22 4500 388062169 CHVBK 20180307125124.0 cr unu---uuuuu 161130e199803 xx s 000 0 eng 10.1079/BJN19980046 doi S0007114598000476 pii (NATIONALLICENCE)cambridge-10.1079/BJN19980046 Periodic fluctuations of gut regulatory peptides in phase with the duodenal migrating myoelectric complex in preruminant calves: effect of different sources of dietary protein [Elektronische Daten] Four preruminant calves with implanted electrodes in the duodenum and a catheter in the external jugular vein were used for investigation of plasma gut regulatory peptide profiles during different phases of migrating myoelectric complex (MMC) in the small intestine. The effects of different dietary proteins on the rhythmic activity of gut peptides and gastrointestinal motility were compared. In particular, the effects of skimmed-milk protein (retaining physiological patterns of abomasal clotting, and abomaso-intestinal digesta flow) v. fish protein (devoid of clotting activity and modifying the digesta flow) were studied. In calves fed on the milk diet, plasma concentrations of pancreatic polypeptide, motilin, secretin, cholecystokinin (CCK) and somatostatin, but not vasoactive intestinal polypeptide or gastrin, fluctuated in phase with the duodenal MMC in the preprandial period. Feeding transiently affected the intestinal MMC and abolished the peptide fluctuations in a specimen-specific manner. In contrast, calves fed on the fish-protein diet showed more profound changes in intestinal MMC. In these animals the MMC-related fluctuations were significant only for plasma CCK. In conclusion, the source of dietary protein has an impact on the physiological endocrine function of the small intestine. Observed fluctuations of plasma gut regulatory peptides seem to be secondary to duodenal motility cycles. Copyright © The Nutrition Society 1998 Gut peptides nationallicence Duodenum nationallicence Myoelectrical activity nationallicence Dietary protein nationallicence Zabielski Romuald Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France Dardillat Claude Station de Recherches sur la Nutrition des Herbivores, INRA, Theix, 63122 Saint-Genès-Champanelle, France Huërou-Luron Isabelle Le Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France Bernard Christine INSERM U45, Hôpital Edouard Herriot, 69374 Lyon, France Chayvialle Jean Alain INSERM U45, Hôpital Edouard Herriot, 69374 Lyon, France Guilloteau Paul Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France British Journal of Nutrition Cambridge University Press 79/3(1998-03), 287-296 0007-1145 79:3<287 1998 79 BJN https://doi.org/10.1079/BJN19980046 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19980046 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zabielski Romuald Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France NATIONALLICENCE 700 1- Dardillat Claude Station de Recherches sur la Nutrition des Herbivores, INRA, Theix, 63122 Saint-Genès-Champanelle, France NATIONALLICENCE 700 1- Huërou-Luron Isabelle Le Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France NATIONALLICENCE 700 1- Bernard Christine INSERM U45, Hôpital Edouard Herriot, 69374 Lyon, France NATIONALLICENCE 700 1- Chayvialle Jean Alain INSERM U45, Hôpital Edouard Herriot, 69374 Lyon, France NATIONALLICENCE 700 1- Guilloteau Paul Laboratoire du Jeune Ruminant, INRA, 65 rue de St Brieuc, 35042 Rennes, France NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 79/3(1998-03), 287-296 0007-1145 79:3<287 1998 79 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge