caa a22 4500 38806241X CHVBK 20180307125124.0 cr unu---uuuuu 161130e199806 xx s 000 0 eng 10.1079/BJN19980087 doi S0007114598000889 pii (NATIONALLICENCE)cambridge-10.1079/BJN19980087 Faecal pH, bile acid and sterol concentrations in premenopausal Indian and white vegetarians compared with white omnivores [Elektronische Daten] Faecal bulk, pH, water content, the concentrations of neutral sterols and bile acids and dietary intakes were measured in twenty-two Indian vegetarian, twenty-two white omnivorous and eighteen white vegetarian premenopausal women. Faecal bulk and water content were greater and pH lower in the Indian vegetarians. Total faecal animal sterol and coprostanol concentrations expressed on a dry-weight basis were lower in the vegetarians compared with the omnivores. The faecal sterol concentrations were correlated with dietary cholesterol intake. Primary bile acids were detected in six Indian vegetarians, two white vegetarians and two white omnivores; secondary bile acids were detected in all the white omnivore and vegetarian subjects but not in two of the Indian vegetarians. Total faecal free bile acid and conjugated bile acid concentrations were lower in the white vegetarians compared with the omnivores. Faecal lithocholic acid concentrations were lower in both Indian and white vegetarians. The lithocholic: deoxycholic acid ratio and coprostanol: total animal sterols ratio were significantly lower in the Indian vegetarians compared with the omnivores. Both ratios were positively correlated with faecal pH. Stepwise multiple regression analyses were undertaken in order to identify which nutrients influenced faecal pH, lithocholic and deoxycholic acid concentrations. The intakes of starch and dietary fibre were negatively associated with faecal concentrations of lithocholic and deoxycholic acid. Starch intake alone was negatively associated with faecal pH. The results of this study confirm that diets high in dietary fibre decrease faecal bile acid concentrations and suggest that the complex carbohydrates present in Indian vegetarian diets influence faecal pH and inhibit the degradation of faecal steroids. Copyright © The Nutrition Society 1998 Bile nationallicence Lithocholic acid nationallicence Deoxycholic acid nationallicence Vegetarians nationallicence Reddy Sheela Nutrition Food & Health Research Centre, King's College London, Campden Hill Road, London W8 7AH, UK Sanders T. A. B. Nutrition Food & Health Research Centre, King's College London, Campden Hill Road, London W8 7AH, UK Owen R. W. PHLS Centre for Applied Microbiology and Research, Sensor Development Group, Porton Down, Salisbury, Wiltshire SP4 OJG, UK Thompson M. H. PHLS Centre for Applied Microbiology and Research, Sensor Development Group, Porton Down, Salisbury, Wiltshire SP4 OJG, UK British Journal of Nutrition Cambridge University Press 79/6(1998-06), 495-500 0007-1145 79:6<495 1998 79 BJN https://doi.org/10.1079/BJN19980087 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19980087 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Reddy Sheela Nutrition Food & Health Research Centre, King's College London, Campden Hill Road, London W8 7AH, UK NATIONALLICENCE 700 1- Sanders T. A. B. Nutrition Food & Health Research Centre, King's College London, Campden Hill Road, London W8 7AH, UK NATIONALLICENCE 700 1- Owen R. W. PHLS Centre for Applied Microbiology and Research, Sensor Development Group, Porton Down, Salisbury, Wiltshire SP4 OJG, UK NATIONALLICENCE 700 1- Thompson M. H. PHLS Centre for Applied Microbiology and Research, Sensor Development Group, Porton Down, Salisbury, Wiltshire SP4 OJG, UK NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 79/6(1998-06), 495-500 0007-1145 79:6<495 1998 79 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge