caa a22 4500 388062827 CHVBK 20180307125126.0 cr unu---uuuuu 161130e199802 xx s 000 0 eng 10.1079/BJN19980025 doi S0007114598000269 pii (NATIONALLICENCE)cambridge-10.1079/BJN19980025 The effect of triacylglycerol-fatty acid positional distribution on postprandial metabolism in subcutaneous adipose tissue [Elektronische Daten] We hypothesized that fatty acids at the sn−2 position of chylomicron triacylglycerol are preferentially released into the venous plasma (rather than being taken up and stored in the adipocytes) after hydrolysis by lipoprotein lipase (EC 3.1.1.34) in adipose tissue. Arterio-venous differences across adipose tissue were studied in eight healthy subjects on two occasions for 6 h after ingestion of different structured triacylglycerols rich in palmitic acid either at the sn−2 or the sn−1,3 positions. In particular the specific fatty acids making up lipoprotein fractions and plasma non-esterified fatty acids were analysed. After the different meals there were no differences between either postprandial arterialized or venous plasma metabolite concentrations. Chylomicron triacylglycerol extraction in adipose tissue was the same following the two types of fat. There was no difference between the specific fatty acid composition of the postprandial non-esterified fatty acid release from adipose tissue after ingestion of the two triacylglycerols, indicating that there was no preferential release of a saturated fatty acid at the sn−2 position. Copyright © The Nutrition Society 1998 Triacylglycerols nationallicence Adipose tissue nationallicence Lipoprotein lipase nationallicence Postprandial metabolism nationallicence Summers Lucinda K. M. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK Fielding Barbara A. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK Ilic Vera Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK Quinlan Paul T. Unilever Research Colworth Laboratory, Colworth House, Sharnbrook, Bedford MK44 1LQ, UK Frayn Keith N. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK British Journal of Nutrition Cambridge University Press 79/2(1998-02), 141-147 0007-1145 79:2<141 1998 79 BJN https://doi.org/10.1079/BJN19980025 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19980025 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Summers Lucinda K. M. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK NATIONALLICENCE 700 1- Fielding Barbara A. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK NATIONALLICENCE 700 1- Ilic Vera Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK NATIONALLICENCE 700 1- Quinlan Paul T. Unilever Research Colworth Laboratory, Colworth House, Sharnbrook, Bedford MK44 1LQ, UK NATIONALLICENCE 700 1- Frayn Keith N. Oxford Lipid Metabolism Group, Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford OX2 6HE, UK NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 79/2(1998-02), 141-147 0007-1145 79:2<141 1998 79 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge