caa a22 4500 388062967 CHVBK 20180307125126.0 cr unu---uuuuu 161130e199811 xx s 000 0 eng 10.1017/S0007114598001500 doi S0007114598001500 pii (NATIONALLICENCE)cambridge-10.1017/S0007114598001500 The effect of short-term calcium supplementation on biochemical markers of bone metabolism in healthy young adults [Elektronische Daten] The influence of Ca supplementation of the usual diet for 14d on biochemical markers of bone turnover was investigated in healthy young adults aged 21-26 years. In a crossover study, eighteen subjects (five male and thirteen female) were randomly assigned to their self-selected diet (about 22 mmol Ca/d) or their self-selected diet with a 20 mmol/d Ca supplement (about 40 mmol Ca/d) for 14d followed by crossover to the alternative diet for a further 14d. During each dietary period fasting morning first void urine samples (last 3d) and fasting blood serum samples (morning of twelfth day) were collected. Ca supplementation reduced urinary excretion of pyridinoline (14%) and deoxypyridinoline (16%) (biochemical markers of bone resorption) but had no effect on biochemical markers of bone formation (serum osteocalcin and bone-specific alkaline phosphatase; EC 3.1.3.1). It is concluded that Ca supplementation of the usual diet in young adults suppresses bone resorption over a 2-week period. If sustained, this could result in suppression of the bone remodelling rate and an increase in bone mass over time. The findings of this short-term study with a relatively small number of young adults highlight the need for a longer-term intervention study of the effect of increased Ca intake on bone mass in this age group. Copyright © The Nutrition Society 1998 Calcium nationallicence Bone nationallicence Biochemical markers nationallicence Young adults nationallicence Ginty Fiona Department of Nutrition, University College, Cork, Ireland Flynn Albert Department of Nutrition, University College, Cork, Ireland Cashman Kevin D. Department of Nutrition, University College, Cork, Ireland British Journal of Nutrition Cambridge University Press 80/5(1998-11), 437-443 0007-1145 80:5<437 1998 80 BJN https://doi.org/10.1017/S0007114598001500 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0007114598001500 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ginty Fiona Department of Nutrition, University College, Cork, Ireland NATIONALLICENCE 700 1- Flynn Albert Department of Nutrition, University College, Cork, Ireland NATIONALLICENCE 700 1- Cashman Kevin D. Department of Nutrition, University College, Cork, Ireland NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 80/5(1998-11), 437-443 0007-1145 80:5<437 1998 80 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge