caa a22 4500 388063548 CHVBK 20180307125128.0 cr unu---uuuuu 161130e199801 xx s 000 0 eng 10.1079/BJN19980013 doi S0007114598000142 pii (NATIONALLICENCE)cambridge-10.1079/BJN19980013 Effects of soya milk and Bifidobacterium-fermented soya milk on plasma and liver lipids, and faecal steroids in hamsters fed on a cholesterol-free or cholesterol-enriched diet [Elektronische Daten] The effects of freeze-dried soya milk (SM) and Bifidobacterium-fermented soya milk (FSM) on plasma and liver lipids, and faecal steroid excretion were estimated in hamsters fed on a cholesterol-free or cholesterol-enriched diet. Hamsters fed on the cholesterol-free diet containing 300 g FSM/kg had lower levels of plasma VLDL + LDL cholesterol than the animals fed on the control diet. SM in the diet produced a similar pattern without significant differences. In the cholesterol-enriched diet group, SM and FSM decreased the levels of plasma total cholesterol and VLDL + LDL-cholesterol. SM and FSM decreased the plasma triacylglycerol level in both the cholesterol-free and -enriched diet groups. The liver total cholesterol contents in the SM and FSM groups were lower than that in the control group, for hamsters fed on the cholesterol-free diet. The liver triacylglycerol content was not modified by SM or FSM in hamsters fed on either the cholesterol-free or -enriched diet. SM and FSM increased the total bile acid excretion and the proportion of cholesterol entering the cholic acid biosynthesis pathway in both the cholesterol-free and -enriched diet groups. SM and FSM did not affect neutral steroid excretion in the cholesterol-free or -enriched diet group. There was an inverse relationship between VLDL + LDL-cholesterol and faecal bile acid excretion in hamsters fed on the cholesterol-free (r −0.670, P < 0.01) and cholesterol-enriched (r −0.761, P < 0.001) diets respectively. These results indicated that SM had an anti-atherogenic effect, and that this effect was not diminished by prior fermentation. Copyright © The Nutrition Society 1998 Soya milk nationallicence Bifidobacterium nationallicence Cholesterol nationallicence Bile acids nationallicence Kikuchi-Hayakawa H. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan Onodera N. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan Matsubara S. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan Yasuda E. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan Shimakawa Y. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan Ishikawa F. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan British Journal of Nutrition Cambridge University Press 79/1(1998-01), 97-105 0007-1145 79:1<97 1998 79 BJN https://doi.org/10.1079/BJN19980013 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1079/BJN19980013 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kikuchi-Hayakawa H. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 700 1- Onodera N. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 700 1- Matsubara S. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 700 1- Yasuda E. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 700 1- Shimakawa Y. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 700 1- Ishikawa F. Yakult Central Institute for Microbiological Research, Kunitachi, Tokyo, Japan NATIONALLICENCE 773 0- British Journal of Nutrition Cambridge University Press 79/1(1998-01), 97-105 0007-1145 79:1<97 1998 79 BJN CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge