caa a22 4500 388072954 CHVBK 20180307125153.0 cr unu---uuuuu 161130e199906 xx s 000 0 eng 10.1017/S0790966700005206 doi S0790966700005206 pii (NATIONALLICENCE)cambridge-10.1017/S0790966700005206 Depot antipsychotic prophylaxis in bipolar affective disorder [Elektronische Daten] [L Mannion, PA Carney, D Sloan, R O'Toole] Objective: Depot antipsychotic medication is often prescribed as maintenance treatment for patients with bipolar affective disorder. In this study we examined the case notes of 14 patients with bipolar disorder who had been prescribed depot antipsychotics. Our aim was to establish the effectiveness of depot medication in this group. Method: We calculated the total number of hospital admissions, length of hospital stay, and total number of affective episodes for each patient from the onset of their illness to the time of the study. The frequency of affective episodes and hospital admission were compared during periods on or off depot medication. Results: Treatment with depot antipsychotics was associated with a significant decrease in the number of hospital admissions, overall affective episodes and manic episodes in particular. Conclusions: Prophylactic treatment with depot antipsychotics may be useful for certain patients with bipolar disorder, in particular those patients who experience frequent manic episodes. Further proof of the efficacy of depot antipsychotics in the prophylaxis of bipolar affective disorder requires the completion of a double-blind prospective trial. Copyright © Cambridge University Press 1999 Bipolar disorder nationallicence Depot nationallicence Prophylactics nationallicence Antipsychotics nationallicence Mannion L. aut Carney PA Department of Psychiatry, University College Hospital, Galway, Ireland aut Sloan D. Department of Psychiatry, University College Hospital, Galway, Ireland aut O'Toole R. Department of Psychiatry, University College Hospital, Galway, Ireland aut Irish Journal of Psychological Medicine Cambridge University Press 16/2(1999-06), 64-66 0790-9667 16:2<64 1999 16 IPM https://doi.org/10.1017/S0790966700005206 text/html Onlinezugriff via DOI 1 conference jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0790966700005206 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mannion L. aut NATIONALLICENCE 700 1- Carney PA Department of Psychiatry, University College Hospital, Galway, Ireland aut NATIONALLICENCE 700 1- Sloan D. Department of Psychiatry, University College Hospital, Galway, Ireland aut NATIONALLICENCE 700 1- O'Toole R. Department of Psychiatry, University College Hospital, Galway, Ireland aut NATIONALLICENCE 773 0- Irish Journal of Psychological Medicine Cambridge University Press 16/2(1999-06), 64-66 0790-9667 16:2<64 1999 16 IPM CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge