caa a22 4500 388073594 CHVBK 20180307125155.0 cr unu---uuuuu 161130e199912 xx s 000 0 eng 10.1017/S0790966700005528 doi S0790966700005528 pii (NATIONALLICENCE)cambridge-10.1017/S0790966700005528 Outcome studies in schizophrenia [Elektronische Daten] Objectives: To outline the limitations of traditional studies of outcome in schizophrenia and to review the findings arising from ‘first episode' psychosis studies. Method: An extensive literature search was performed and relevant papers were examined and analysed. Results: Current knowledge regarding outcome predictors in schizophrenia has primarily been derived from a series of ‘consecutive admission' and ‘long-term follow-back' studies. However, methodological considerations may limit the generalisability of these studies' findings. The prospective evaluation of first episode cohorts has advanced our knowledge regarding the relative importance of premorbid and intercurrent factors in determining outcome in schizophrenia. Conclusions: To date, the ‘first episode' strategy has highlighted some potentially clinically modifiable outcome predictors. These findings may open the way for targeted introduction of measures aimed at preventing poor outcomes in schizophrenia. Copyright © Cambridge University Press 1999 Schizophrenia nationallicence Outcome studies nationallicence Methodological limitations nationallicence First episode nationallicence Browne Stephen Department of Psychiatry, Waterford Regional Hospital, Dunmore Road, Waterford, Ireland. Larkin Conall St John of God Hospital, Stillorgan, Co Dublin, Ireland. O'Callaghan Eadbhard Cluain Mhuire Family Centre, Newtownpark Avenue, Blackrock, Co Dublin, Ireland. Irish Journal of Psychological Medicine Cambridge University Press 16/4(1999-12), 140-144 0790-9667 16:4<140 1999 16 IPM https://doi.org/10.1017/S0790966700005528 text/html Onlinezugriff via DOI 1 review-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0790966700005528 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Browne Stephen Department of Psychiatry, Waterford Regional Hospital, Dunmore Road, Waterford, Ireland NATIONALLICENCE 700 1- Larkin Conall St John of God Hospital, Stillorgan, Co Dublin, Ireland NATIONALLICENCE 700 1- O'Callaghan Eadbhard Cluain Mhuire Family Centre, Newtownpark Avenue, Blackrock, Co Dublin, Ireland NATIONALLICENCE 773 0- Irish Journal of Psychological Medicine Cambridge University Press 16/4(1999-12), 140-144 0790-9667 16:4<140 1999 16 IPM CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge