caa a22 4500 388083034 CHVBK 20180307125223.0 cr unu---uuuuu 161130e199903 xx s 000 0 eng 10.1017/S0022215100143610 doi S0022215100143610 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100143610 Transtympanic dexamethasone application in Ménière's disease: an alternative treatment for intractable vertigo [Elektronische Daten] The aetiology of Ménière's disease still remains unknown and its therapy is therefore empirical. As a result of immunological abnormalities demonstrated, steroids are commonly used in Ménière's disease. The place of topical steroids is still controversial. In this investigation topical dexamethasone is applied for three months through a ventilation tube in patients with intractable vertigo. The results showed that this treatment controls vertigo in 72 per cent of cases. No patient was worse than before treatment. Only in 17 per cent of the patients was there an increase in hearing level. When compared to the reports which used only tympanostomy tubes, this procedure seems to have a placebo effect with minimal harmful effects. It appears that transtympanic dexamethasone application is a good alternative to vestibular nerve section. Topical treatment may be sufficient in most patients. Systemic treatment may be used in patients where topical treatment fails. Copyright © JLO (1984) Limited 1999 Ménière's disease nationallicence Steroids nationallicence Transtympanic dexamethasone nationallicence Vertigo nationallicence Sennaroğlu Levent Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey. Mottaghian Dini Farzin Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey. Sennaroğlu Gonca Department of Audiology and Speech Pathology Section, Hacettepe University Faculty of Medicine, Ankara, Turkey. Gursel Bulent Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey. Ozkan Soner Department of Audiology and Speech Pathology Section, Hacettepe University Faculty of Medicine, Ankara, Turkey. The Journal of Laryngology & Otology Cambridge University Press 113/3(1999-03), 217-221 0022-2151 113:3<217 1999 113 JLO https://doi.org/10.1017/S0022215100143610 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100143610 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sennaroğlu Levent Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey NATIONALLICENCE 700 1- Mottaghian Dini Farzin Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey NATIONALLICENCE 700 1- Sennaroğlu Gonca Department of Audiology and Speech Pathology Section, Hacettepe University Faculty of Medicine, Ankara, Turkey NATIONALLICENCE 700 1- Gursel Bulent Department of Otolaryngology, Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey NATIONALLICENCE 700 1- Ozkan Soner Department of Audiology and Speech Pathology Section, Hacettepe University Faculty of Medicine, Ankara, Turkey NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/3(1999-03), 217-221 0022-2151 113:3<217 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge