caa a22 4500 388083301 CHVBK 20180307125223.0 cr unu---uuuuu 161130e199902 xx s 000 0 eng 10.1017/S0022215100143373 doi S0022215100143373 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100143373 Juvenile angiofibroma: the lessons of 20 years of modern imaging [Elektronische Daten] Seventy-two patients with juvenile angiofibroma have been investigated by computerized tomography (CT) and/or magnetic resonance imaging (MRI) over a period of 20 years. The evidence from these studies indicates that angiofibroma takes origin in the pterygo-palatine fossa at the aperture of the pterygoid (vidian) canal. An important extension of the tumour is posteriorly along the pterygoid canal with invasion of the cancellous bone of the pterygoid base, and greater wing of the sphenoid (60 per cent of patients). Distinctive features of angiofibroma are the high recurrence rate, and the rapidity with which many tumours recur. It is postulated that the principle determinant of recurrence is a high tumour growth rate at the time of surgery coupled with incomplete surgical excision. The inability to remove the tumour in toto is principally due to deep invasion of the sphenoid, as described above. In this series 93 per cent of recurrences occurred withthis type of tumour extension. A contributory cause in these patients is the use of pre-operative embolization. The treatment implications of these findings are examined. Copyright © JLO (1984) Limited 1999 Angiofibroma nationallicence Tomography scanners, X-ray computed nationallicence Magnetic resonance imaging nationallicence Lloyd Glyn The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK. Howard David The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK. Phelps Peter The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK. Cheesman Anthony The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK. The Journal of Laryngology & Otology Cambridge University Press 113/2(1999-02), 127-134 0022-2151 113:2<127 1999 113 JLO https://doi.org/10.1017/S0022215100143373 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100143373 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lloyd Glyn The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK NATIONALLICENCE 700 1- Howard David The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK NATIONALLICENCE 700 1- Phelps Peter The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK NATIONALLICENCE 700 1- Cheesman Anthony The Royal National Throat, Nose and Ear Hospital, Gray's Inn Road, London, UK NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/2(1999-02), 127-134 0022-2151 113:2<127 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge