caa a22 4500 388083867 CHVBK 20180307125225.0 cr unu---uuuuu 161130e199906 xx s 000 0 eng 10.1017/S0022215100144457 doi S0022215100144457 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100144457 The diagnostic value of positron emission tomography (PET) with radiolabelled fluorodeoxyglucose (18F-FDG) in head and neck cancer [Elektronische Daten] Positron emission tomography (PET) scanning has recently been introduced into clinical practice but its usefulness in the management of head and neck cancer is not well defined. The aim of this prospective preliminary study was to examine the clinical value of fluorodeoxyglucose (FDG) - PET in patients with head and neck cancer treated by radiotherapy with surgery in reserve by (i) relating quantitative uptake of isotope to tumour type and histological grade and (ii) comparing the imaging findings of PET and magnetic resonance imaging (MRI) in post-radiotherapy assessment of tumour response. Twenty-one patients had pre-treatment PET and MRI scans and these were repeated four and eight months after treatment if there was no clinical relapse. Pre-treatment uptake of FDG using tumour to cerebellar ratio parameters was significantly related to the histological grade of squamous cancer (p = 0.04) but not to tumour type. Discordance of post-treatment PET/MRI findings in one case indicates a possible role for PET in the early detection of tumour recurrence. Other potential uses of PET scanning in the management of head and neck cancer are discussed. Copyright © JLO (1984) Limited 1999 Tomography, emission-computed nationallicence Head and neck neoplasms nationallicence Slevin N. J. Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK. Collins C. D. Department of Diagnostic Radiology, Christie Hospital NHS Trust, Manchester, UK. Hastings D. L. Department of Medical Physics, Christie Hospital NHS Trust, Manchester, UK. Waller M. L. Department of Medical Physics, Christie Hospital NHS Trust, Manchester, UK. Johnson R. J. Department of Diagnostic Radiology, Christie Hospital NHS Trust, Manchester, UK. Cowan R. A. Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK. Birzgalis A. R. Department of Surgery, Christie Hospital NHS Trust, Manchester, UK. Farrington W. T. Department of Surgery, Christie Hospital NHS Trust, Manchester, UK. Swindell R. Department of Medical Statistics, Christie Hospital NHS Trust, Manchester, UK. The Journal of Laryngology & Otology Cambridge University Press 113/6(1999-06), 548-554 0022-2151 113:6<548 1999 113 JLO https://doi.org/10.1017/S0022215100144457 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100144457 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Slevin N. J. Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Collins C. D. Department of Diagnostic Radiology, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Hastings D. L. Department of Medical Physics, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Waller M. L. Department of Medical Physics, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Johnson R. J. Department of Diagnostic Radiology, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Cowan R. A. Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Birzgalis A. R. Department of Surgery, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Farrington W. T. Department of Surgery, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 700 1- Swindell R. Department of Medical Statistics, Christie Hospital NHS Trust, Manchester, UK NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/6(1999-06), 548-554 0022-2151 113:6<548 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge