caa a22 4500 388084561 CHVBK 20180307125226.0 cr unu---uuuuu 161130e199904 xx s 000 0 eng 10.1017/S0022215100143920 doi S0022215100143920 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100143920 Effect of caffeine on the vocal folds: a pilot study [Elektronische Daten] Caffeine is considered to be a dehydrating agent with detrimental effects on the quality of voice of persons ingesting it. This has led medical personnel dealing with voice disorders, especially in the case of professional voice users, to give advice against the use of caffeine. Yet this is an anecdotal truth as an extensive Medline literature search did not reveal any scientific evidence of caffeine being proven to have adverse effects on the vocal folds. We, therefore, initiated this pilot study to ascertain the connection between caffeine and voice quality on a laboratory basis. Two hundred and fifty mg of caffeine were provided to eight volunteers in tablet form, and blood levels along with laryngograph readings were recorded to document the changes produced. Analysing the irregularities of frequencies in a) free speech b) a reading passage and c) singing ‘Happy Birthday', substantial changes were seen to authenticate the fact that caffeine does produce alterations in voice quality but these alterations have considerable intrasubject variability. A full study with wider parameters is to be performed on this subject as we consider it to be of importance in the management of voice disorders. Copyright © JLO (1984) Limited 1999 Caffeine nationallicence Dehydration nationallicence Vocal fold nationallicence Akhtar S. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK. Wood G. Department of Speech and Language Therapy, Royal National Throat, Nose and Ear Hospital, London, UK. Rubin J. S. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK. O'Flynn P. E. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK. Ratcliffe P. Department of Speech and Language Therapy, Royal National Throat, Nose and Ear Hospital, London, UK. The Journal of Laryngology & Otology Cambridge University Press 113/4(1999-04), 341-345 0022-2151 113:4<341 1999 113 JLO https://doi.org/10.1017/S0022215100143920 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100143920 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Akhtar S. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK NATIONALLICENCE 700 1- Wood G. Department of Speech and Language Therapy, Royal National Throat, Nose and Ear Hospital, London, UK NATIONALLICENCE 700 1- Rubin J. S. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK NATIONALLICENCE 700 1- O'Flynn P. E. Department of Otolaryngology/Head and Neck Surgery, Royal National Throat, Nose and Ear Hospital, London, UK NATIONALLICENCE 700 1- Ratcliffe P. Department of Speech and Language Therapy, Royal National Throat, Nose and Ear Hospital, London, UK NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/4(1999-04), 341-345 0022-2151 113:4<341 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge