caa a22 4500 388085541 CHVBK 20180307125229.0 cr unu---uuuuu 161130e199911 xx s 000 0 eng 10.1017/S0022215100145748 doi S0022215100145748 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100145748 A morphological and morphometric study of the peripheral process of the human vestibular nerve following posterior cranial fossa neurectomy [Elektronische Daten] Three vestibular nerve specimens removed at transmeatal neurectomy were studied in order to understand better retrograde degeneration and regeneration after vestibular neurectomy in the posterior cranial fossa. In two cases this procedure followed retrolabyrinthine retrosigmoid posterior fossa vestibular neurectomy. The subjects, three patients with Menière's disease, were compared with one another and two autopsy controls with no known otological problem. The specimens were obtained at the distal end of the internal auditory canal and transversely sectioned. Many collapsed Schwann cell basement membranes were observed. The ratio of small-diameter nerve fibres increased significantly after neurectomy. Onion bulb formation around myelinated nerve fibres with small diameters and Schwann cell proliferation around the soma of vestibular ganglion cells reflected remyelination. We conclude that peripheral processes of vestibular nerve fibres can undergo retrograde degeneration and subsequent regeneration after transection of the central process. Copyright © JLO (1984) Limited 1999 Vestibular nerve nationallicence Surgery, operative nationallicence Nerve degeneration nationallicence Nerve regeneration nationallicence Kitamura Ken Departments of Otolaryngology, School of Medicine, Tokyo Medical and Dental University, Tokyo. Takahashi Katsumasa Departments of Otolaryngology, School of Medicine, Jichi Medical School, Tochigi-ken, Japan. Kakoi Hiroyuki Departments of Otolaryngology, School of Medicine, Jichi Medical School, Tochigi-ken, Japan. Sugimoto Taro Departments of Otolaryngology, School of Medicine, Tokyo Medical and Dental University, Tokyo. Silverstein Herbert Ear Research Foundation, Sarasota, FL, USA. The Journal of Laryngology & Otology Cambridge University Press 113/11(1999-11), 967-972 0022-2151 113:11<967 1999 113 JLO https://doi.org/10.1017/S0022215100145748 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100145748 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kitamura Ken Departments of Otolaryngology, School of Medicine, Tokyo Medical and Dental University, Tokyo NATIONALLICENCE 700 1- Takahashi Katsumasa Departments of Otolaryngology, School of Medicine, Jichi Medical School, Tochigi-ken, Japan NATIONALLICENCE 700 1- Kakoi Hiroyuki Departments of Otolaryngology, School of Medicine, Jichi Medical School, Tochigi-ken, Japan NATIONALLICENCE 700 1- Sugimoto Taro Departments of Otolaryngology, School of Medicine, Tokyo Medical and Dental University, Tokyo NATIONALLICENCE 700 1- Silverstein Herbert Ear Research Foundation, Sarasota, FL, USA NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/11(1999-11), 967-972 0022-2151 113:11<967 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge