caa a22 4500 388085835 CHVBK 20180307125229.0 cr unu---uuuuu 161130e199910 xx s 000 0 eng 10.1017/S002221510014558X doi S002221510014558X pii (NATIONALLICENCE)cambridge-10.1017/S002221510014558X Presumed reduction of vestibular function in unilateral Menière's disease with aminoglycoside eardrops [Elektronische Daten] We report the first case in the world literature of deliberate ablation of vestibular function in unilateral Meniere's disease with aminoglycoside eardrops (Garasone). These findings give conclusive proof that Garasone eardrops, and by implication, all topical aminoglycoside ear drops can be vestibulotoxic in the presence of a tympanic membrane defect. The lower concentration of gentamicin in Garasone, in comparison to the standard intratympanic preparations for chemical ablation of vestibular function, may also offer a reduction in the potential risk of cochleotoxocity. Copyright © JLO (1984) Limited 1999 Aminoglycosides nationallicence Menière's disease nationallicence Vertigo nationallicence Disease management nationallicence Bath Andrew P. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada Walsh Rory M. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada Bance Manohar L. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada The Journal of Laryngology & Otology Cambridge University Press 113/10(1999-10), 916-918 0022-2151 113:10<916 1999 113 JLO https://doi.org/10.1017/S002221510014558X text/html Onlinezugriff via DOI 1 other jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S002221510014558X text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bath Andrew P. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada NATIONALLICENCE 700 1- Walsh Rory M. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada NATIONALLICENCE 700 1- Bance Manohar L. Department of Otolaryngology, The Toronto Hospital, Toronto, Ontario, Canada NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/10(1999-10), 916-918 0022-2151 113:10<916 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge