caa a22 4500 388086122 CHVBK 20180307125230.0 cr unu---uuuuu 161130e199905 xx s 000 0 eng 10.1017/S0022215100144147 doi S0022215100144147 pii (NATIONALLICENCE)cambridge-10.1017/S0022215100144147 Topical inhalant steroid (budesonide, Pulmicort® nasal) therapy in intubation granuloma [Elektronische Daten] Intubation granuloma of the larynx is an iatrogenic disease which is induced by endotracheal intubation. It has basically been managed by conservative medical treatment with observation. Surgical excision can be considered as a last resort due to the high recurrence rate which subjects the patients to repeated anaesthesia. The purpose of this study is to evaluate the therapeutic effect of topical steroid in intubation granuloma, comparing the results of conservative medical treatment with, or without, surgery (Group I, 14 patients) and inhalant therapy with topical budesonide (Group II, 20 patients). In Group I, complete disappearance of granuloma occurred in six cases within a year (42.8 per cent) with conservative therapy only. Microlaryngeal surgery was performed on the eight cases of persisting granuloma after conservative therapy for a year, resulting in two cases of recurrence. In Group II, the granuloma disappeared completely in 85 per cent within six months and in 95 per cent within 12 months without any remarkable side-effects. We concluded that intubation granuloma of the larynx could be treated with topical inhalant steroid as the first choice of therapy rather than other medical treatment or surgical intervention. Copyright © JLO (1984) Limited 1999 Intubation, endotracheal nationallicence Granuloma nationallicence Drug therapy nationallicence Roh Hwan-Jung Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea. Goh Eui-Kyung Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea. Chon Kyong-Myong Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea. Wang Soo-Geun Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea. The Journal of Laryngology & Otology Cambridge University Press 113/5(1999-05), 427-432 0022-2151 113:5<427 1999 113 JLO https://doi.org/10.1017/S0022215100144147 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0022215100144147 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Roh Hwan-Jung Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea NATIONALLICENCE 700 1- Goh Eui-Kyung Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea NATIONALLICENCE 700 1- Chon Kyong-Myong Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea NATIONALLICENCE 700 1- Wang Soo-Geun Department of Otolaryngology, College of Medicine, Pusan National University, Pusan, Korea NATIONALLICENCE 773 0- The Journal of Laryngology & Otology Cambridge University Press 113/5(1999-05), 427-432 0022-2151 113:5<427 1999 113 JLO CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge