caa a22 4500 388096217 CHVBK 20180307125304.0 cr unu---uuuuu 161130e199905 xx s 000 0 eng 10.1017/S1092852900011731 doi S1092852900011731 pii (NATIONALLICENCE)cambridge-10.1017/S1092852900011731 Identification of Attention-Deficit/Hyperactivity Disorder Pedigrees and Substance Use Disorder Pedigrees Through an ADHD Proband Sample [Elektronische Daten] Substance use disorder (SUD) pedigrees identified through an attention deficit/hyperactivity disorder (ADHD) proband may be helpful in teasing apart the genetic risks for both ADHD and SUD (ie, alcohol or drug use). Pedigrees segregating for both SUD and ADHD may represent a subset of both of these common disorders that share a related genetic basis. We determined the number of SUD and ADHD pedigrees in a sample of 175 ADHD probands. We found 52 ADHD pedigrees, indicating that at least 29.7% were familial cases. We also found 50 SUD pedigrees; 13 families contained both an alcohol and a drug pedigree, 35 families were alcohol-only pedigrees, and two families were drug-only pedigrees. The incidence of drug-only pedigrees is significantly higher (P<0.01) in families with familial ADHD. This was also true for families with both drug and alcohol pedigrees (P<0.01). The total number of SUD pedigrees and the families with alcohol-alone pedigrees were not significantly different in ADHD pedigrees compared with nonfamilial ADHD families. Copyright © Cambridge University Press 1999 Bauer Amy Ram Ranga Schindler Kim M. Pato Michele T. Macciardi Fabio Gnagy Elizabeth Burrows-MacLean Lisa Pelham William Pato Carlos N. CNS Spectrums Cambridge University Press 4/5(1999-05), 55-58 1092-8529 4:5<55 1999 4 CNS https://doi.org/10.1017/S1092852900011731 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S1092852900011731 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bauer Amy NATIONALLICENCE 700 1- Ram Ranga NATIONALLICENCE 700 1- Schindler Kim M. NATIONALLICENCE 700 1- Pato Michele T. NATIONALLICENCE 700 1- Macciardi Fabio NATIONALLICENCE 700 1- Gnagy Elizabeth NATIONALLICENCE 700 1- Burrows-MacLean Lisa NATIONALLICENCE 700 1- Pelham William NATIONALLICENCE 700 1- Pato Carlos N. NATIONALLICENCE 773 0- CNS Spectrums Cambridge University Press 4/5(1999-05), 55-58 1092-8529 4:5<55 1999 4 CNS CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge