caa a22 4500 388096411 CHVBK 20180307125305.0 cr unu---uuuuu 161130e199908 xx s 000 0 eng 10.1017/S0029665199000877 doi S0029665199000877 pii (NATIONALLICENCE)cambridge-10.1017/S0029665199000877 Jackson Malcom J. Department of Medicine, University of Liverpool, Liverpool L69 3GA, UK Free radicals in skin and muscle: damaging agents or signals for adaptation? [Elektronische Daten] [Malcom J. Jackson] Much of the current literature regarding the biological effects of antioxidant nutrients has concentrated on their potential role in inhibiting or preventing tissue damage induced by free radical species produced during metabolism. Recent findings indicate that antioxidants may also have more subtle roles, regulating changes in gene expression induced by oxidizing free radical species. There is increasing evidence that free radicals act as signals for cell adaptation in a variety of cell types and the nature of the mechanisms by which free radical species influence gene expression is the subject of much current research. Processes such as these may be particularly important in tissues regularly exposed to varying amounts of oxidative stress as part of their normal physiological functions. Examples of such tissues include skin exposed to u.v. light and skeletal muscle subjected to repeated bouts of exercise. Copyright © The Nutrition Society 1999 Antioxidants nationallicence Oxidative stress nationallicence Free radicals nationallicence Skeletal muscle nationallicence Skin nationallicence Proceedings of the Nutrition Society Cambridge University Press 58/3(1999-08), 673-676 0029-6651 58:3<673 1999 58 PNS https://doi.org/10.1017/S0029665199000877 text/html Onlinezugriff via DOI 1 conference jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0029665199000877 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Jackson Malcom J. Department of Medicine, University of Liverpool, Liverpool L69 3GA, UK NATIONALLICENCE 773 0- Proceedings of the Nutrition Society Cambridge University Press 58/3(1999-08), 673-676 0029-6651 58:3<673 1999 58 PNS CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge