caa a22 4500 388096616 CHVBK 20180307125305.0 cr unu---uuuuu 161130e199908 xx s 000 0 eng 10.1017/S0029665199000701 doi S0029665199000701 pii (NATIONALLICENCE)cambridge-10.1017/S0029665199000701 French Stephen J. Centre for Human Nutrition, University of Sheffield, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK The effects of specific nutrients on the regulation of feeding behaviour in human subjects [Elektronische Daten] [Stephen J. French] Regulation of short-term energy intake involves the balance of positive drives to eat arising from the sight, smell and palatability of food with negative feedback signals from learned associations, gastrointestinal and metabolic signals. The stomach and small intestine are major sites in the feedback inhibition of food intake and subsequent period of appetite suppression. The present paper reviews the evidence that not only does the nature of the regulatory signal suppressing food intake depend on the type and energy content of nutrient consumed, but also the specific chemical composition of the nutrients and the site at which they are delivered. It is evident that feedback inhibition of feeding can be modulated by the particular chemical structure of nutrients (e.g. specific sugar or triacylglycerol structures). These differences in response are likely to be a consequence of differences in physical properties of particular nutrients depending on their chemical structure, and may also result from different receptor affinities for specific dietary structures. Moreover, the site of administration of nutrients can also profoundly affect the size and nature of the subsequent feeding response, suggesting that feed-forward interactions occur between the taste of foods and gastrointestinal stimulation. Copyright © The Nutrition Society 1999 Appetite nationallicence Gastrointestinal function nationallicence Macronutrients nationallicence Proceedings of the Nutrition Society Cambridge University Press 58/3(1999-08), 533-540 0029-6651 58:3<533 1999 58 PNS https://doi.org/10.1017/S0029665199000701 text/html Onlinezugriff via DOI 1 conference jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0029665199000701 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- French Stephen J. Centre for Human Nutrition, University of Sheffield, Northern General Hospital, Herries Road, Sheffield S5 7AU, UK NATIONALLICENCE 773 0- Proceedings of the Nutrition Society Cambridge University Press 58/3(1999-08), 533-540 0029-6651 58:3<533 1999 58 PNS CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge