caa a22 4500 388096977 CHVBK 20180307125306.0 cr unu---uuuuu 161130e199905 xx s 000 0 eng 10.1017/S0029665199000622 doi S0029665199000622 pii (NATIONALLICENCE)cambridge-10.1017/S0029665199000622 Optimal nutrition: calcium, magnesium and phosphorus [Elektronische Daten] In the past, a major challenge for nutrition research was in defining indicators of nutritional adequacy. More recently, the research base related to the role of nutrition in chronic disease has expanded sufficiently to permit moving beyond deficiency indicators to other indicators with broader functional significance. Thus, nutrition research is faced with the new challenge of defining ‘optimal nutrition'. One definition of optimal nutrition with respect to any particular nutrient could be when a functional marker reaches an ‘optimal value' or plateau beyond which it is no longer affected by intake or stores of the nutrient. A functional marker of nutrient status could be defined as a physiological or biochemical factor which (1) is related to function or effect of the nutrient in target tissue(s) and (2) is affected by dietary intake or stores of the nutrient (which may include markers of disease risk). Examples of such indicators or markers are those related to risk of chronic diseases such as osteoporosis, CHD, or hypertension. The present review focuses on the concept of optimal nutrition with respect to three nutrients, Ca, Mg and P. However, for P and Mg there are as yet no functional indicators which respond to dietary intake, and in such cases nutrient requirements are established using more traditional approaches, e.g. balance data. For Ca, there has been interest in using maximal Ca retention, which is based on balance data, bone mass measurements and biomarkers of bone turnover as useful functional indicators of the adequacy of Ca intake. Copyright © The Nutrition Society 1999 Calcium nationallicence Magnesium nationallicence Phosphorus nationallicence Functional markers nationallicence Cashman Kevin D. Department of Nutrition, University College, Cork, Republic of Ireland Flynn Albert Department of Nutrition, University College, Cork, Republic of Ireland Proceedings of the Nutrition Society Cambridge University Press 58/2(1999-05), 477-487 0029-6651 58:2<477 1999 58 PNS https://doi.org/10.1017/S0029665199000622 text/html Onlinezugriff via DOI 1 conference jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0029665199000622 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Cashman Kevin D. Department of Nutrition, University College, Cork, Republic of Ireland NATIONALLICENCE 700 1- Flynn Albert Department of Nutrition, University College, Cork, Republic of Ireland NATIONALLICENCE 773 0- Proceedings of the Nutrition Society Cambridge University Press 58/2(1999-05), 477-487 0029-6651 58:2<477 1999 58 PNS CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge