caa a22 4500 388097175 CHVBK 20180307125307.0 cr unu---uuuuu 161130e199905 xx s 000 0 eng 10.1017/S0029665199000609 doi S0029665199000609 pii (NATIONALLICENCE)cambridge-10.1017/S0029665199000609 Optimal nutrition: vitamin E [Elektronische Daten] Interest in the role of vitamin E in disease prevention has encouraged the search for reliable indices of vitamin E status. Most studies in human subjects make use of static markers, usually a-tocopherol concentrations in plasma or serum. Plasma or serum α-tocopherol concentrations of < 11.6, 11.6-16.2, and > 16.2 mmol/l are normally regarded as indicating deficient, low and acceptable vitamin E status respectively, although more recently it has been suggested that the optimal plasma α-tocopherol concentration for protection against cardiovascular disease and cancer is > 30 μmol/l at common plasma lipid concentrations in combination with plasma vitamin C concentrations of > 50 μmol/l and > 0.4 mmol β-carotene/l. Assessment of vitamin E status has also been based on α-tocopherol concentrations in erythrocytes, lymphocytes, platelets, lipoproteins, adipose tissue, buccal mucosal cells and LDL, and on α- tocopherol: γ-tocopherol in serum or plasma. Erythrocyte susceptibility to haemolysis or lipid oxidation, breath hydrocarbon exhalation, oxidative resistance of LDL, and α-tocopheryl quinone concentrations in cerebrospinal fluid have been used as functional markers of vitamin E status. However, many of these tests tend to be non-specific and poorly standardized. The recognition that vitamin E has important roles in platelet, vascular and immune function in addition to its antioxidant properties may lead to the identification of more specific biomarkers of vitamin E status. Copyright © The Nutrition Society 1999 Vitamin E nationallicence Biomarkers nationallicence Morrissey P. A. Department of Nutrition, University College, Cork, Republic of Ireland Sheehy P. J. A. Department of Nutrition, University College, Cork, Republic of Ireland Proceedings of the Nutrition Society Cambridge University Press 58/2(1999-05), 459-468 0029-6651 58:2<459 1999 58 PNS https://doi.org/10.1017/S0029665199000609 text/html Onlinezugriff via DOI 1 conference jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0029665199000609 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Morrissey P. A. Department of Nutrition, University College, Cork, Republic of Ireland NATIONALLICENCE 700 1- Sheehy P. J. A. Department of Nutrition, University College, Cork, Republic of Ireland NATIONALLICENCE 773 0- Proceedings of the Nutrition Society Cambridge University Press 58/2(1999-05), 459-468 0029-6651 58:2<459 1999 58 PNS CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge