caa a22 4500 388111011 CHVBK 20180307125353.0 cr unu---uuuuu 161130e199912 xx s 000 0 eng 10.1017/S0924270800035870 doi S0924270800035870 pii (NATIONALLICENCE)cambridge-10.1017/S0924270800035870 White P.D. Chronic unexplained fatigue [Elektronische Daten] [P.D. White] Fatigue is a common symptom in the community and the commonest associations are with stress or mood disturbance. One in a hundred people complain of unexplained and prolonged fatigue, with half that number meeting the strictest criteria for the chronic fatigue syndrome (CFS). Discrete fatigue syndromes have been described, particularly after Epstein Barr virus infection. The majority of patients with CFS have a syndrome similar to the ICD-10 definition of neurasthenia. Mood and somatoform disorders are common comorbid or differential diagnoses. The prognosis is poor, particularly in patients attending hospitals and those with comorbid psychiatric disorders. The aetiology of both CFS and chronic unexplained fatigue are essentially unknown, perhaps reflecting the heterogenenous natures of both the symptom and syndrome. There is reasonable evidence to suggest that particular infections may trigger both prolonged fatigue and CFS. Maintaining factors are different from triggering factors and include mood and sleep disorders, illness beliefs and behaviours, and possibly inactivity. Treatments aimed at reversing these maintaining factors show promise. Copyright © Cambridge University Press 1999 Fatigue nationallicence chronic fatigue syndrome nationallicence nosology nationallicence aetiology nationallicence prognosis nationallicence treatments nationallicence Acta Neuropsychiatrica Cambridge University Press 11/4(1999-12), 130-133 0924-2708 11:4<130 1999 11 NEU https://doi.org/10.1017/S0924270800035870 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1017/S0924270800035870 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- White P.D. NATIONALLICENCE 773 0- Acta Neuropsychiatrica Cambridge University Press 11/4(1999-12), 130-133 0924-2708 11:4<130 1999 11 NEU CC0 http://creativecommons.org/publicdomain/zero/1.0 nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-cambridge